Austrian Registry for Evaluation of Treatment Patterns and Outcome in Patients With Advanced Pancreatic Ductal Adenocarcinoma (PDAC)

NCT ID: NCT05526443

Last Updated: 2025-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-13

Study Completion Date

2027-09-30

Brief Summary

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To systematically collect and analyse real-world data on treatment patterns, clinical outcomes and toxicities among patients with advanced pancreatic ductal adenocarcinoma (PDAC) undergoing systematic treatment in Austria

Detailed Description

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1500 adult patients with locally advanced inoperable and/or metastasized PDAC undergoing first line chemotherapy

Conditions

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Pancreatic Cancer Advanced Pancreatic Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient with locally advanced inoperable and/or metastatic pancreatic ductal adenocarcinoma

Patient with locally advanced inoperable and/or metastatic pancreatic ductal adenocarcinoma

all approved chemotherapeutic agents from second line

Intervention Type DRUG

all approved chemotherapeutic agents from second line

Interventions

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all approved chemotherapeutic agents from second line

all approved chemotherapeutic agents from second line

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 18 years, female and male
* ECOG (Eastern Cooperative Oncology Group) Scale 0-2
* Diagnosis of histologically confirmed locally advanced inoperable and/or metastatic PDAC
* Patients undergoing palliative 1st line therapy with a platinum- or gemcitabine- based chemotherapy in case of previous (neo)adjuvant therapy also patients who receive nal-Irinotecan/5-FU/Leukovorin as palliative first line are eglible
* Signed informed consent for prospective patients, for retrospective cases no informed consent is required

Exclusion Criteria

* Patients with locally advanced operable PDAC who do not receive palliative chemotherapy
* Patients with locally advanced borderline resectable PDAC who do not receive palliative chemotherapy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Graz

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jakob Riedl, Priv.Doz. Dr.

Role: PRINCIPAL_INVESTIGATOR

Medical University of Graz

Locations

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Medical University Graz Department of Oncology

Graz, Styria, Austria

Site Status RECRUITING

Ordensklinikum Linz

Linz, Upper Austria, Austria

Site Status RECRUITING

Landesklinikum Amstetten

Amstetten, , Austria

Site Status RECRUITING

Landesklinikum Feldkirch

Feldkirch, , Austria

Site Status RECRUITING

Krankenhaus der Barmherzigen Brüder

Graz, , Austria

Site Status RECRUITING

Universitätsklinikum Innsbruck,

Innsbruck, , Austria

Site Status RECRUITING

Landesklinikum Klagenfurt

Klagenfurt, , Austria

Site Status RECRUITING

Universitätsklinikum St. Pölten

Sankt Pölten, , Austria

Site Status RECRUITING

Barmherzige Schwestern Krankenhaus Wien

Vienna, , Austria

Site Status RECRUITING

Pancreatic Cancer Unit des Comprehensive Cancer Center (CCC-PCU)

Vienna, , Austria

Site Status RECRUITING

St. Josef Krankenhaus Wien

Vienna, , Austria

Site Status RECRUITING

Krankenhaus St. Vinzenz Zams

Zams, , Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Armin Gerger, Univ.Prof.Dr

Role: CONTACT

+43 316 385 13115

Karin Groller, MPH

Role: CONTACT

+43 316 385 14174

Facility Contacts

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Florian Moik, Dr.Dr.

Role: primary

+43 316 385 31490

Karin Groller, MPH

Role: backup

+43 316 385 14174

Holger Rumpold, PD MD

Role: primary

Armin Gerger, Univ. Prof. Dr.

Role: primary

Thomas Winder, PD. Dr.

Role: primary

Daniel Mayer, Dr.

Role: primary

Role: backup

Angela Djanani, Dr.

Role: primary

Wolfgang Eisterer, Univ. Prof. Dr.

Role: primary

Role: backup

Hossein Taghizadeh, Dr. PhD

Role: primary

Leopold Öhler, Univ. Prof. Dr.

Role: primary

Gerald Prager, Assoz. Prof. PD. Dr.

Role: primary

Leopold Öhler, Univ. Prof. Dr.

Role: primary

Ewald Wöll, Univ.Prof. Dr.

Role: primary

Other Identifiers

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ADPACA

Identifier Type: -

Identifier Source: org_study_id

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