Cardio-Oncology Rehabilitation Exercise

NCT ID: NCT05522959

Last Updated: 2025-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-14

Study Completion Date

2026-12-31

Brief Summary

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Women with breast cancer who are referred to the cardiac rehabilitation program at the Toronto Rehabilitation Institute will be invited to enrol in this observational study. Participants will take part in an established 16-week multimodal cardiac rehabilitation program (HEALTh program) at Toronto Rehabilitation Institute and outcome measures will be assessed before and after program participation to determine the effectiveness of the program in improving cardio metabolic health. Change in VO₂peak will be assessed using Cardiopulmonary Exercise Test (CPET). Traditional cardiac risk factors, lifestyle behaviours, exercise adherence, health-related quality of life, and fatigue will also be assessed.

Detailed Description

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Conditions

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Breast Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* History of early-stage breast cancer (I-III)
* Currently receiving or have completed adjuvant therapy (i.e. chemotherapy, surgery, radiation, targeted therapies)
* Able to communicate in English

Exclusion Criteria

* Pregnancy
* Metastatic disease (Stage IV)
* Unable or unwilling to complete cardiopulmonary exercise test
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Toronto Rehabilitation Institute

OTHER

Sponsor Role collaborator

University of Toronto

OTHER

Sponsor Role lead

Responsible Party

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Amy Kirkham

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Amy Kirkham, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Toronto

Locations

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Toronto Rehabilitation Institute

Toronto, Ontario, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Amy A Kirkham, PhD

Role: CONTACT

(416) 946-4069‬‬

Facility Contacts

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Paul Oh, MD

Role: primary

Other Identifiers

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19-5080

Identifier Type: -

Identifier Source: org_study_id

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