Investigating the Effects of Cardiac Rehabilitation eXercise Modalities on Physical and Mental Health Outcomes

NCT ID: NCT02765568

Last Updated: 2020-10-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

135 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-30

Study Completion Date

2019-10-16

Brief Summary

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Coronary revascularization improves survival for patients with coronary artery disease. However,many patients are left with poor physical and mental health. Traditional cardiac rehabilitation involves moderate intensity continuous exercise (MICE). Alternatives to traditional cardiac rehabilitation programming may however provide superior understudied benefits to patients with poor physical and mental health. Nordic walking (NW) and high-intensity interval training (HIIT) are two examples of alternative programs for cardiac rehabilitation, which may provide superior physical and mental health benefits when compared to traditional MICE. The main purpose of this project is, therefore, to determine the short and long term physical and mental health benefits of alternative cardiac rehabilitation modalities, including NW and HIIT on exercise capacity, quality of life and depression after a 12-week program.

Detailed Description

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Conditions

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Coronary Artery Disease (CAD)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Moderate Intensity Continuous Exercise

Moderate Intensity Continuous Exercise Training

Group Type EXPERIMENTAL

Moderate Intensity Continuous Exercise Training

Intervention Type BEHAVIORAL

Participants will complete supervised exercise sessions. Moderate-intensity continuous exercise training will follow cardiovascular rehabilitation guidelines. Participants will attend on-site moderate-intensity continuous exercise training two times weekly for 12 weeks.

Nordic Walking

Nordic Walking

Group Type EXPERIMENTAL

Nordic Walking

Intervention Type BEHAVIORAL

Participants will complete supervised exercise sessions. Participants will attend on-site Nordic walking training two times weekly for 12 weeks

High Intensity Interval Training

High Intensity Interval Training

Group Type EXPERIMENTAL

High Intensity Interval Training

Intervention Type BEHAVIORAL

Participants will complete supervised exercise sessions. Participants will attend on-site high-intensity interval training two times weekly for 12 weeks

Interventions

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High Intensity Interval Training

Participants will complete supervised exercise sessions. Participants will attend on-site high-intensity interval training two times weekly for 12 weeks

Intervention Type BEHAVIORAL

Moderate Intensity Continuous Exercise Training

Participants will complete supervised exercise sessions. Moderate-intensity continuous exercise training will follow cardiovascular rehabilitation guidelines. Participants will attend on-site moderate-intensity continuous exercise training two times weekly for 12 weeks.

Intervention Type BEHAVIORAL

Nordic Walking

Participants will complete supervised exercise sessions. Participants will attend on-site Nordic walking training two times weekly for 12 weeks

Intervention Type BEHAVIORAL

Other Intervention Names

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HIIT MICE NW

Eligibility Criteria

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Inclusion Criteria

* Patient with CAD who recently underwent PCI (within 2-10 weeks) PCI or coronary artery bypass grafting (within the last 18 weeks);
* Patient is referred to University of Ottawa Heart Institute cardiac rehabilitation program;
* Patient is able to walk independently
* Patient is willing to attend an onsite cardiac rehabilitation program twice weekly for 12 weeks;
* At least 40 years of age;
* Patient is willing and able to provide informed consent

Exclusion Criteria

* Currently participating in routine exercise training (\>2x/week) and/or using Nordic Walking poles;
* Active infection or inflammatory condition;
* Over 75 years of age;
* Persistent or permanent atrial fibrillation;
* Pregnant, lactating or planning to become pregnant during the trial period;
* Unstable angina or established diagnosis of chronic obstructive pulmonary disease, severe mitral or aortic stenosis, or hypertrophic obstructive cardiomyopathy;
* Unable to read and understand English or French;
* Unwilling or unable to return for follow-up visit at weeks 12 and 26;
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ontario Ministry of Health and Long Term Care

OTHER_GOV

Sponsor Role collaborator

Heart and Stroke Foundation of Canada

OTHER

Sponsor Role collaborator

Ottawa Heart Institute Research Corporation

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jennifer L Reed, PhD

Role: PRINCIPAL_INVESTIGATOR

Ottawa Heart Institute Research Corporation

Locations

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University of Ottawa Heart Insititue

Ottawa, Ontario, Canada

Site Status

Countries

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Canada

References

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Marcal IR, Cotie LM, Ribeiro I, Reed JL. The Effects of Different Exercise Modalities and Intensities on Arterial Stiffness in Patients With Coronary Artery Disease. J Cardiopulm Rehabil Prev. 2023 Sep 1;43(5):384-385. doi: 10.1097/HCR.0000000000000799. Epub 2023 May 15. No abstract available.

Reference Type DERIVED
PMID: 37184470 (View on PubMed)

Garneau L, Terada T, Mistura M, Mulvihill EE, Reed JL, Aguer C. Exercise training reduces circulating cytokines in male patients with coronary artery disease and type 2 diabetes: A pilot study. Physiol Rep. 2023 Mar;11(5):e15634. doi: 10.14814/phy2.15634.

Reference Type DERIVED
PMID: 36905198 (View on PubMed)

Other Identifiers

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20160127-01H

Identifier Type: -

Identifier Source: org_study_id