Comparison of Low and Normal Flow Anesthesia in Robotic Assisted Radical Prostatectomy

NCT ID: NCT05517551

Last Updated: 2022-08-26

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 68 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-08-31
• Study Completion Date: 2023-03-31

Brief Summary

Robot-assisted laparoscopic radical prostatectomy has gained increasing popularity compared to open radical prostatectomy with its advantages such as low blood loss, reduced blood transfusion rate, low complication rate, and shortened hospital stay. Since robot-assisted laparoscopic radical prostatectomy should be performed in the limited retroperitoneal area, insufflation of the abdomen with carbon dioxide (CO2) (pneumoperitoneum) and steep Trendelenburg position are required to provide better surgical vision.

Low-flow anesthesia warms and moistens the inhaled gases, creating a more physiological breathing atmosphere during anesthesia. In addition, it provides cost advantage by reducing inhalation agent consumption and reduces atmospheric pollution. Studies show that long-term minimal flow anesthesia is safe and advantageous for non-laparoscopic surgery.

The aim of this study is to compare low-flow (1L/min) with normal flow (3lt/min) desflurane anesthesia in terms of hemodynamic and respiratory parameters, inhalation agent consumption and soda lime consumption for robotic assisted laparoscopic radical prostatectomy surgery.

The secondary aim of the study is to compare the effects of low-flow and normal-flow anesthesia in the steep trendelenburg position (45°) used for robotically assisted laparoscopic radical prostatectomy.

Conditions

Low Flow Anesthesia; Normal Flow Anesthesia; Robotic Surgery

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

normal flow anesthesia

A fresh gas flow of 3 L/min will be applied continuously

robotic assisted radical prostatectomy

Intervention Type: PROCEDURE

Patients who will undergo robotic-assisted laparoscopic prostatectomy surgery

low flow anesthesia

A fresh gas flow of 3 L/min will be applied for the first 20 minutes after intubation , and then it will be reduced to 1 L/min.

robotic assisted radical prostatectomy

Intervention Type: PROCEDURE

Patients who will undergo robotic-assisted laparoscopic prostatectomy surgery

Interventions

robotic assisted radical prostatectomy

Patients who will undergo robotic-assisted laparoscopic prostatectomy surgery

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• ASA I-II risk group

Exclusion Criteria

• ASA III, IV, V,
• concomitant serious cardiac, respiratory, hepatic, renal disturbance,
• mental status disorder and hearing problem,
• anxiety and depression and/or other psychiatric disorders,
• patient's refusal

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Ankara City Hospital Bilkent

OTHER

Sponsor Role: lead

Responsible Party

Betül Güven

Principle Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Ankara City Hospital

Ankara, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Central Contacts

betül güven aytaç, MD

Role: CONTACT

drbguven@hotmail.com

05073578351

Other Identifiers

E1-22-2755

Identifier Type: -

Identifier Source: org_study_id