Hyperglycaemia and Hyperlactataemia in Patients With Severe Acute Brain Injury
NCT ID: NCT05505396
Last Updated: 2025-07-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
459 participants
OBSERVATIONAL
2022-10-24
2024-10-30
Brief Summary
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Additionally, in a subgroup of patients undergoing advanced multimodal neuromonitoring on either clinical or research indication, the relationship between hyperglycaemia and brain glucose levels as well as systemic and microdialysis lactate will be examined.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Sampling of blood and cerebrospinal fluid
Blood HbA1c, insulin, C-peptide and IL-6 measured at admission. Glucose and lactate measured every 4 hours during intensive care stay. Daily sampling of CSV analysed for glucose and lactate in patients with EVD.
Eligibility Criteria
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Inclusion Criteria
* Admission to the neurointensive care unit at Rigshospitalet
* Diagnosis of acute brain injury categorised as TBI, SAH, ICH, ischaemic stroke, or other conditions
Exclusion Criteria
* Closest relatives do not understand written and spoken Danish or English
18 Years
ALL
No
Sponsors
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Rigshospitalet, Denmark
OTHER
Responsible Party
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Alexandra Vassilieva
Principal Investigator
Locations
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Department of Neuroanesthesiology and Neurointensive Care, Rigshospitalet
Copenhagen, , Denmark
Countries
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Other Identifiers
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P-2022-321
Identifier Type: -
Identifier Source: org_study_id
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