Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis
NCT ID: NCT05502835
Last Updated: 2023-01-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
90 participants
INTERVENTIONAL
2022-08-20
2023-01-25
Brief Summary
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Detailed Description
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Group A ;( control group) Forty five patients will do elective open colonic mass resection and anastomosis. Infusion of 6 ml/kg/hr. Ringer's solution.
Group B; Forty five patients will do elective open colonic mass resection and anastomosis. Infusion of 2 ml/kg/hr. Ringer's solution guided by pulse pressure variation.
Intraoperative fluid volume, hemodynamics, serum lactate and intestinal edema will be measured after induction of anesthesia and every hour till the end of the operation, length of the hospital stay, first time to gastrointestinal motion and postoperative complications are recorded.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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conventional fluid management group
patients will do elective open colonic mass resection and anastomosis will receive Infusion of 6 ml/kg/hr. Ringer's solution.
conventional fluid management
Infusion of 6 ml/kg/hr. Ringer's solution.
ppv group
patients will do elective open colonic mass resection and anastomosis. Infusion of 2 ml/kg/hr. Ringer's solution guided by pulse pressure variation.
pulse pressure variation
Infusion of 2 ml/kg/hr. Ringer's solution guided by pulse pressure variation.
Interventions
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pulse pressure variation
Infusion of 2 ml/kg/hr. Ringer's solution guided by pulse pressure variation.
conventional fluid management
Infusion of 6 ml/kg/hr. Ringer's solution.
Eligibility Criteria
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Inclusion Criteria
* Patients scheduled for elective open colonic mass resection and anastomosis.
Exclusion Criteria
* Peripheral artery disease.
* An ejection fraction below 30%.
* A pulmonary pathology.
18 Years
70 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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RAMY AHMED
Assistant Professor of Anesthesia
Locations
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Ain shams university
Cairo, , Egypt
Countries
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Other Identifiers
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IRB00006379 GUT OEDEMA
Identifier Type: -
Identifier Source: org_study_id
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