Erector Spinae Plane Block in Laparoscopic Colorectal Cancer Surgery
NCT ID: NCT07297433
Last Updated: 2025-12-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
60 participants
INTERVENTIONAL
2025-12-20
2026-04-15
Brief Summary
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Detailed Description
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The erector spinae plane block (ESP) is a block that is easy to perform with ultrasound (USG) guidance and has a relatively low risk of mechanical complications. It has quickly become popular and is used in various indications in anesthesiology and resuscitation clinics.
The total number of volunteers expected to participate in this study is 60. Patients will be randomly assigned to two groups using a sealed envelope method. The number of volunteers determined for each group is 30.
Patients will be interviewed before the operation and informed about the operation and the procedure to be performed. After reading and approving the informed consent form, patients to be included in the study will be divided into two groups using the sealed envelope method. Group 1 will receive ESP block, while Group 2 will be the control group and will not receive any block.
All patients will be monitored throughout the operation using invasive blood pressure, ECG, and pulse oximetry. Following preoxygenation, induction will be administered with intravenous propofol (2 mg/kg), fentanyl 1 µg/kg, and rocuronium (0.6 mg/kg) injections. After tracheal intubation, an arterial catheter will be placed in the radial artery to continuously monitor blood pressure. Anesthesia maintenance will be achieved with inhaled sevoflurane and intravenous remifentanil infusion. After induction, patients will be placed in the left-right lateral decubitus position, and bilateral blocks will be performed with ultrasound guidance.
Group 1: ESP block, 0.5% bupivacaine 0.2-0.4 ml/kg will be administered. Group 2: Patient group without block.
After ESBP application, the 'Near infrared spectroscopy' device will be placed on the bilateral 9-10th posterior costal region (flank region) of the patients in a manner suitable for observing renal blood flow. Monitoring will be performed throughout the operation and recorded on the follow-up form. N-GAL, serum creatinine, and eGFR values will be measured in both groups during the preoperative and postoperative periods (at 2, 6, and 24 hours).
Once the expected number of patients is reached, the data obtained will be statistically evaluated and recorded.
After the data is collected, it will be processed for statistical evaluation.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Intervention group
Patients will be informed about the operation and the procedure to be performed during a preoperative consultation. Patients included in the study will be taken to the operating room after reading and signing the informed consent form. Bilateral erector spinae plane block will be administered to patients in this group prior to surgery. Renal blood flow will be monitored using NIRS. Postoperative period: NGAL, serum creatinine, and eGFR values will be measured at 2, 6, and 24 hours.
Erector Spinae Plane Block
The erector spinae plane block (ESP) is a block that is easy to perform with ultrasound (USG) guidance and has a relatively low risk of mechanical complications. It has quickly become popular and is used in various indications in anesthesiology and resuscitation clinics.
Control group
Patients will be interviewed before surgery and informed about the surgery and the procedure to be performed. Patients to be included in the study will be taken to the operating room after reading and approving the informed consent form. Patients in this group will not undergo erector spinae plane block. Renal blood flow will be monitored using NIRS. In the postoperative period, NGAL, serum creatinine, and eGFR values will be measured at 2, 6, and 24 hours.
No interventions assigned to this group
Interventions
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Erector Spinae Plane Block
The erector spinae plane block (ESP) is a block that is easy to perform with ultrasound (USG) guidance and has a relatively low risk of mechanical complications. It has quickly become popular and is used in various indications in anesthesiology and resuscitation clinics.
Eligibility Criteria
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Inclusion Criteria
* Colorectal cancer surgery must be planned by a physician
* No infection in the injection site
* No history of any disease related to clotting or bleeding time
* The patient must be a volunteer
* No history of local anesthetic allergy
Exclusion Criteria
* Having a systemic infection or infection at the injection site
* Having any disease related to bleeding time and clotting
* Having a history of local anesthetic allergy
* Patient refusal (ESPB for analgesic purposes)
* Patients with a Body Mass Index (BMI) of 30 or above
18 Years
75 Years
ALL
No
Sponsors
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Kayseri City Hospital
OTHER_GOV
Responsible Party
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Arif Enes Koyuncu
Research assistant doktor
Principal Investigators
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Günhan Gökahmetoğlu
Role: PRINCIPAL_INVESTIGATOR
Kayseri City Hospital
Central Contacts
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Other Identifiers
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KayseriCH-AAR-AEK-01
Identifier Type: -
Identifier Source: org_study_id