The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement
NCT ID: NCT05487053
Last Updated: 2025-03-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
220 participants
INTERVENTIONAL
2024-02-03
2028-07-01
Brief Summary
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Femoral nerve block (FNB) is the "gold standard" for continuous postoperative analgesia after total knee replacement, as it is effective in reducing the frequency of use of opioid analgetics and reduce the duration of hospitalization. At the same time, the negative effect of this method is the motor blockade of the quadriceps femoris muscle which leads to functional impairment and is associated with an increased risk of falling.
Adductor canal block (ACB) provides adequate analgesia comparable to femoral nerve block. Moreover, ACB doesn't affect the motor function of the quadriceps femoris muscle.
The possibility of enhanced recovery after total knee replacement is the reason to compare single-shot adductor canal block and continuous femoral nerve block.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Single-shot adductor canal block
Single-shot adductor canal block
Postoperative analgesia in this group will be carried out by a single-shot bolus of 20 ml Ropivacaine 0.5% in the region of the middle third of the adductor canal.
Continuous femoral nerve block
Continuous femoral nerve block
Postoperative analgesia in this group will be carried out by continuous infusion of local anesthetics through a catheter installed to the femoral nerve in the area of the femoral triangle. Ropivacaine 0.2% solution will be used for postoperative analgesia. Local anesthetic infusion rate is 4 ml/h to 10 ml/h.
Interventions
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Single-shot adductor canal block
Postoperative analgesia in this group will be carried out by a single-shot bolus of 20 ml Ropivacaine 0.5% in the region of the middle third of the adductor canal.
Continuous femoral nerve block
Postoperative analgesia in this group will be carried out by continuous infusion of local anesthetics through a catheter installed to the femoral nerve in the area of the femoral triangle. Ropivacaine 0.2% solution will be used for postoperative analgesia. Local anesthetic infusion rate is 4 ml/h to 10 ml/h.
Eligibility Criteria
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Inclusion Criteria
* Planned primary total knee replacement
* Planned neuraxial anesthesia
* Written informed consent
Exclusion Criteria
* Planned revision total knee replacement
* Known allergic reaction to anesthetics
* Confirmed localized infection at the puncture sites
* Confirmed localized tumor at the puncture sites
* Peripheral neuropathy of the lower extremities
* Parkinson's disease
* Previously enrolled in this trial
18 Years
ALL
No
Sponsors
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Negovsky Reanimatology Research Institute
OTHER_GOV
Responsible Party
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Valery Likhvantsev, MD
Head of the Research V. Negovsky Reanimatology Research Institute
Principal Investigators
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Valery Likhvantsev
Role: PRINCIPAL_INVESTIGATOR
Negovsky Reanimatology Research Institute
Locations
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Clinical Hospital on Yauza
Moscow, , Russia
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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AdORe - ACB
Identifier Type: -
Identifier Source: org_study_id
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