Study of Let-7a and miRNA-124 in Cases of Non-Hodgkin's Lymphoma and Acute Leukemia
NCT ID: NCT05477667
Last Updated: 2022-07-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
100 participants
INTERVENTIONAL
2022-10-01
2023-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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control group
the patients with non-malignant hematological diseases
real time pcr
Detection of expressin level of MiRNA-124 and let-7a using real time pcr
the cases (A)
NHL .
real time pcr
Detection of expressin level of MiRNA-124 and let-7a using real time pcr
the cases (B)
acute leukemia
real time pcr
Detection of expressin level of MiRNA-124 and let-7a using real time pcr
Interventions
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real time pcr
Detection of expressin level of MiRNA-124 and let-7a using real time pcr
Eligibility Criteria
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Inclusion Criteria
* patient with NHL and acute leukemia .
Exclusion Criteria
* patient on chemotherapy
1 Year
80 Years
ALL
No
Sponsors
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Sohag University
OTHER
Responsible Party
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Sara Talal Mahmoud
assisstent professor at clinical pathology department at faculty of medicine sohag university hospital
Locations
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Sohag University Hospital
Sohag, , Egypt
Countries
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Central Contacts
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rania M bakry, professor
Role: CONTACT
Facility Contacts
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Osama R Elshrif, professor
Role: primary
References
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Armitage JO, Gascoyne RD, Lunning MA, Cavalli F. Non-Hodgkin lymphoma. Lancet. 2017 Jul 15;390(10091):298-310. doi: 10.1016/S0140-6736(16)32407-2. Epub 2017 Jan 31.
Bedewy AML, Elmaghraby SM, Shehata AA, Kandil NS. Prognostic Value of miRNA-155 Expression in B-Cell Non-Hodgkin Lymphoma. Turk J Haematol. 2017 Aug 2;34(3):207-212. doi: 10.4274/tjh.2016.0286. Epub 2017 Feb 1.
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep 12.
Fuertes T, Ramiro AR, de Yebenes VG. miRNA-Based Therapies in B Cell Non-Hodgkin Lymphoma. Trends Immunol. 2020 Oct;41(10):932-947. doi: 10.1016/j.it.2020.08.006. Epub 2020 Sep 1.
Other Identifiers
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Soh-Med-22-7-22
Identifier Type: -
Identifier Source: org_study_id
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