Inflammatory Biomarkers for the Diagnosis of oPRES

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

621 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-01

Study Completion Date

2022-07-31

Brief Summary

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The purpose of this study is to explore the inflammatory biomarkers for the diagnosis of obstetric posterior reversible encephalopathy syndrome.

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Detailed Description

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The investigators retrospectively collected data (General information, clinical data, biochemical indicators, imaging features, and pregnancy outcome) from pregnant woman diagnosed with PRES to explore the inflammatory biomarkers for the diagnosis of oPRES during 2012 to 2021.Then, the investigators grouped all the patients into PRES group (PE or E with PRES) and NOT-PRES group (PE or E without PRES) according to the diagnostic criteria of PRES. Then, the investigators analysed the inflammatory biomarkers, such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR), and so on of two groups, and compared the difference of tow groups.

Conditions

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Posterior Reversible Encephalopathy Syndrome Inflammatory Biomarkers Neutrophil-lymphocyte Ratio

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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PRES group

patients in PE or E with PRES

Whether the PE or E patient combined with PRES

Intervention Type OTHER

According to the Diagnostic criteria of PRES, all the patients grouped into two groups.

NON-PRES group

patients in PE or E without PRES

No interventions assigned to this group

Interventions

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Whether the PE or E patient combined with PRES

According to the Diagnostic criteria of PRES, all the patients grouped into two groups.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Pregnant women were diagnosed of PE or E.
2. All patients were examined the cranial imaging (MRI or CT), and imaging findings meeting the diagnostic criteria of PRES or normal.
3. all patients provided written informed consent.