Stockholm Myocardial Infarction with Nonobstructive Coronaries Study 3

NCT ID: NCT05426408

Last Updated: 2025-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

85 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-01

Study Completion Date

2026-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The present pilot study will investigate the prevalence of CMD in an unselected cohort of patients with the working diagnosis MINOCA and to study if the diagnostic yield can be improved by adding adenosine to the CMR investigation. Patient will be their own controls.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Myocardial Infarction with Nonobstructive Coronary Arteries

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Patients will be their own controls
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

The investigators who will perform the evaluation of the CMR investigations will be blinded to all clinical data.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients with MINOCA undergoing CMR

Patients will be their own controls

Group Type OTHER

Cardiac magnetic resonance imaging to study coronary microvascular dysfunction

Intervention Type DIAGNOSTIC_TEST

Myocardial perfusion mapping will be investigated after administration of adenosine

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cardiac magnetic resonance imaging to study coronary microvascular dysfunction

Myocardial perfusion mapping will be investigated after administration of adenosine

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* a suspected diagnosis of MINOCA or takotsubo syndrome with coronary angiography without diameter stenosis ≥50%
* age 35-80 years
* reading and writing proficiency in Swedish

Exclusion Criteria

* Claustrofobia
* Arrythmia and/or pacemaker (atrial fibrillation and AV-block I- III)
* Asthma or severe chronic obstructive lung disease
* eGFR \< 30 ml/min
* spontaneous coronary artery dissection
* acute pulmonary embolism
* acute myocardial infarction type 2
* cardiomyopathy other than takotsubo syndrome
* a previous myocardial infarction due to CAD
Minimum Eligible Age

35 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Region Stockholm

OTHER_GOV

Sponsor Role collaborator

Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Per Tornvall

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Per Tornvall, MD

Role: PRINCIPAL_INVESTIGATOR

Karolinska Instítutet

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Per Tornvall

Stockholm, , Sweden

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Sweden

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Per Tornvall, MD

Role: CONTACT

+468616100

Peder Sörensson, MD

Role: CONTACT

+46812370000

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Per Tornvall

Role: primary

+46722180560

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

SMINC-3

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Dobutamine vs Adenosine CMR Study
NCT03661827 COMPLETED NA
Mechanocardiography in Patients With STEMI
NCT03441724 ACTIVE_NOT_RECRUITING