ACBT and High Frequency Chest Wall Oscillations in COPD Patients

NCT ID: NCT05424133

Last Updated: 2023-01-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-15

Study Completion Date

2022-10-31

Brief Summary

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Chronic obstructive pulmonary disease (COPD) patients with mucus hyper secretion tend to demonstrate increased frequency of infective exacerbations and a steeper slope of decline in lung function. Enhanced mucosal clearance with high frequency chest wall oscillation (HFCWO) devices previously used in cystic fibrosis and bronchiectasis patients may offer the opportunity for community based, self-managed therapy to improve quality of life and lung function. The aim of this study is to compare effects of active cycle of breathing and high frequency chest wall oscillations in chronic obstructive pulmonary disease .This study will be a Randomized Clinical trial and will be conducted at Physical Therapy Department of DHQ Hospital NAROWAL. The study will be completed within the time duration of six months. Consecutive sampling technique will be used to collect the data. A sample size of Total 42 patients will be taken in this study. Patients will be divided into two groups. BODE Index will be used as outcome measurement tool. Group A will receive the Active cycle of breathing technique and it will performed twice a day for 4 week intervention period for 20 minutes. Group B will receive high frequency chest wall oscillations at 13-15Hz oscillating frequency for 20 minutes twice a day for 4 weeks. The collected data will be analyzed on SPSS - 25.

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Active cycle of breathing technique

Group A will receive Active cycle of breathing technique with routine chest physiotherapy.

Group Type EXPERIMENTAL

Active cycle of breathing

Intervention Type OTHER

Active cycle of breathing technique and it will performed twice a day for 4 week intervention period for 20 minutes

High frequency chest wall oscillation

Group B will receive High frequency chest wall oscillations with routine chest physiotherapy

Group Type ACTIVE_COMPARATOR

High frequency chest wall oscillation

Intervention Type OTHER

High frequency chest wall oscillations at 13-15Hz oscillating frequency for 20 minutes twice a day for 4 weeks.

Interventions

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High frequency chest wall oscillation

High frequency chest wall oscillations at 13-15Hz oscillating frequency for 20 minutes twice a day for 4 weeks.

Intervention Type OTHER

Active cycle of breathing

Active cycle of breathing technique and it will performed twice a day for 4 week intervention period for 20 minutes

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient with clear consciousness ,stable vital sign, and ability to cooperate
* Stage 3-4 COPD according to GOLD criteria
* Adult patients
* Patient who had given informed consent

Exclusion Criteria

* Need for invasive mechanical ventilation
* Active lung tuberculosis
* Chest wall trauma
* Thoracic or abdominal operations in last three months.
* Presence of cardiac pacemaker, artificial stunt or heart failure
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Riphah International University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sidra Afzal, PP-DPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

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DHQ Hospital Narowal

Narowal, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

References

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Shen M, Li Y, Ding X, Xu L, Li F, Lin H. Effect of active cycle of breathing techniques in patients with chronic obstructive pulmonary disease: a systematic review of intervention. Eur J Phys Rehabil Med. 2020 Oct;56(5):625-632. doi: 10.23736/S1973-9087.20.06144-4. Epub 2020 May 13.

Reference Type BACKGROUND
PMID: 32397703 (View on PubMed)

Barto TL, Maselli DJ, Daignault S, Stiglich J, Porter J, Kraemer C, Hansen G. Real-life experience with high-frequency chest wall oscillation vest therapy in adults with non-cystic fibrosis bronchiectasis. Ther Adv Respir Dis. 2020 Jan-Dec;14:1753466620932508. doi: 10.1177/1753466620932508.

Reference Type BACKGROUND
PMID: 32538317 (View on PubMed)

Ntritsos G, Franek J, Belbasis L, Christou MA, Markozannes G, Altman P, Fogel R, Sayre T, Ntzani EE, Evangelou E. Gender-specific estimates of COPD prevalence: a systematic review and meta-analysis. Int J Chron Obstruct Pulmon Dis. 2018 May 10;13:1507-1514. doi: 10.2147/COPD.S146390. eCollection 2018.

Reference Type BACKGROUND
PMID: 29785100 (View on PubMed)

Weycker D, Hansen GL, Seifer FD. Outcomes with high-frequency chest wall oscillation among patients with non-CF bronchiectasis or COPD. American Thoracic Society. 2017. 7. Sievert CE, Beaner BCA, Sievert C. Using High Frequency Chest Wall Oscillation in a Bronchiectasis Patient Population: An Outcomes-Based Case Review. Respiratory Therapy. 2016;10:01.

Reference Type BACKGROUND

Allam NM, Badawy MM. Does High-Frequency Chest Wall Oscillation Have an Impact on Improving Pulmonary Function in Patients With Smoke Inhalation Injury? J Burn Care Res. 2021 Mar 4;42(2):300-304. doi: 10.1093/jbcr/iraa147.

Reference Type BACKGROUND
PMID: 32860696 (View on PubMed)

Gonzalez-Bellido V, Velaz-Baza V, Blanco-Moncada E, Del Carmen Jimeno Esteo M, Cuenca-Zaldivar JN, Colombo-Marro A, Donadio MVF, Torres-Castro R. Immediate Effects and Safety of High-Frequency Chest Wall Compression Compared to Airway Clearance Techniques in Non-Hospitalized Infants With Acute Viral Bronchiolitis. Respir Care. 2021 Mar;66(3):425-433. doi: 10.4187/respcare.08177. Epub 2020 Nov 3.

Reference Type BACKGROUND
PMID: 33144386 (View on PubMed)

Shen MD, Guo LR, Li YW, Gao RT, Sui X, Du Z, Xu LQ, Shi HY, Ni YY, Zhang X, Pang Y, Zhang W, Yu TZ, Li F. Role of the active cycle of breathing technique combined with phonophoresis for the treatment of patients with chronic obstructive pulmonary disease (COPD): study protocol for a preliminary randomized controlled trial. Trials. 2021 Mar 23;22(1):228. doi: 10.1186/s13063-021-05184-x.

Reference Type BACKGROUND
PMID: 33757568 (View on PubMed)

Other Identifiers

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REC/RCR & AHS/22/0321

Identifier Type: -

Identifier Source: org_study_id

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