Effect of HFCWO Vests on Spirometry Measurements

NCT ID: NCT03628456

Last Updated: 2019-11-22

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-13

Study Completion Date

2019-07-02

Brief Summary

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The impact of high-frequency chest wall oscillation therapy on spirometry values (Forced Expiratory Volume, Forced Vital Capacity, Peak Expiratory Flow, Forced Expiratory Flow and Tidal Volume is investigated during use of several products and comparing to baseline values

Detailed Description

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The study will be broken into one (1) arm:

• AffloVest® \& Monarch™

Within the arm, the order of products will be randomized.

Baseline spirometry (Forced Expiratory Volume (FEV1), Forced Vital Capacity (FVC), Peak Expiratory Flow (PEF), Forced Expiratory Flow (FEF25-75%) and Tidal Volume (TV)) will be taken at the beginning, middle and end of each series of measurements with each subject, without any device on the subject. A product (AffloVest or Monarch) will be placed onto subject and turned ON to the highest frequency and intensity settings. Then the subject will be given a certain period of time to adjust and spirometry measurements will then be repeated, then the product will be removed and the subject will be allowed a recovery period, then the other product will be placed on the subject, turned ON and spirometry measurements will repeated.

Conditions

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Cystic Fibrosis Bronchiectasis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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AffloVest Monarch Arm

Devices placed on highest intensity / highest frequency

Group Type EXPERIMENTAL

International Biophysics AffloVest

Intervention Type DEVICE

High-frequency chest wall oscillation vest

Hill-Rom Monarch

Intervention Type DEVICE

High-frequency chest wall oscillation vest

Interventions

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International Biophysics AffloVest

High-frequency chest wall oscillation vest

Intervention Type DEVICE

Hill-Rom Monarch

High-frequency chest wall oscillation vest

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- Healthy subject, ages 18 - 50

Exclusion Criteria

* Non-ambulatory
* diagnosed neuromuscular disorder
* currently using any type of oscillation vest therapy
* diagnosed co-morbid condition (i.e. lung cancer, other lung disorder or disease)
* currently enrolled in a medical research study
* non-English speaking
* presence of the following active implantable devices: pacemakers, neurostimulators, infusion pumps, circulatory support devices, implantable cardioverter defibrillators (ICD's), cochlear implants
* presence of head and/or neck injury that has not yet been stabilized
* presence of active hemorrhage with hemodynamic instability
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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International Biophysics Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thomas W O'Brien, MD

Role: PRINCIPAL_INVESTIGATOR

PDS Research

Locations

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PDS Research

Kissimmee, Florida, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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2018-01

Identifier Type: -

Identifier Source: org_study_id

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