Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD
NCT ID: NCT06578156
Last Updated: 2024-12-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2024-12-12
2027-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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Nasal High Flow Cannula
Nasal High Flow cannula at 70 liters per minute for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to Nasal Low Flow Cannula at less than or equal to 4 liters per minute with supplemental oxygen for 30 minutes
Nasal High Flow Cannula
High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
Nasal Low Flow Cannula
Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times
Nasal Low Flow Cannula
Low Flow Nasal Cannula at less than or equal to 4 liters per minute with supplemental oxygen at patient's baseline for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to High Flow Cannula at 70 liters per minute for 30 minutes
Nasal High Flow Cannula
High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
Nasal Low Flow Cannula
Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times
Interventions
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Nasal High Flow Cannula
High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
Nasal Low Flow Cannula
Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times
Eligibility Criteria
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Inclusion Criteria
* Age 18 years or older
* Diagnosis of COPD
* Ability to ambulate without assistance
* Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all
Exclusion Criteria
* Being on bedrest
* Inability to consent or cooperate with the study
* Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime
* Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)
* Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)
18 Years
100 Years
ALL
No
Sponsors
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American Thoracic Society
OTHER
University of Miami
OTHER
Responsible Party
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Saramaria Afanador Castiblanco
Assistant Professor
Principal Investigators
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Saramaria Afanador Castiblanco, M.D.
Role: PRINCIPAL_INVESTIGATOR
University of Miami
Locations
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University of Miami
Miami, Florida, United States
Countries
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Central Contacts
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Facility Contacts
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Saramaria Afanador Castiblanco, M.D.
Role: primary
Other Identifiers
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20240476
Identifier Type: -
Identifier Source: org_study_id