New Serum Biomarkers for Monitoring Early Diagnosis of Ovarian Cancer Recurrence

NCT ID: NCT05410028

Last Updated: 2022-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-03

Study Completion Date

2026-03-03

Brief Summary

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In this study, mass spectrometry was used to analyze immune inflammation-related protein complexes, post-translational modified glycopeptide omics and tumor-related metabolomics in serum, respectively, in order to find potential metabolic small molecule biomarkers or marker profiles that can be used for early diagnosis of cancer recurrence.

Detailed Description

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Time cohort study: patients with confirmed ovarian epithelial cancer at different time cutoff points before treatment, after surgery, during chemotherapy, and after chemotherapy, until clinically confirmed patients relapse. At least 50 patients are expected to be enrolled.

Conditions

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Ovarian Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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No intervention in clinical treatment

No intervention in clinical treatment

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Female
* A diagnosed patient with epithelial ovarian cancer
* Age ≤ 70

Exclusion Criteria

* Male
* Suffering from other malignant tumors
* Non-compliant patient
* Age above 70
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Peng Peng, MD

Role: CONTACT

+86-13521361934

Facility Contacts

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Peng Peng

Role: primary

+86-13521361934

Other Identifiers

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PUMCH-OC2

Identifier Type: -

Identifier Source: org_study_id

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