The Role of CircDENND4C in Epithelial Ovarian Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-01

Study Completion Date

2028-10-01

Brief Summary

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circular RNAs (circRNAs), a newly discovered type of endogenous noncoding RNAs \[8\], are involved in the regulation of various biological functions. They act by sponging off certain microRNAs (miRNAs) and play a role in the pathogenesis of many diseases, including cancers \[9-11\]. In addition, circRNAs are not com- monly degraded by RNA enzymes present in body flu- ids \[8\], and most of them possess expression specificity at the tissue, cell, and developmental stage level \[12,13\]. Thus, they can be ideal clinica

Detailed Description

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epithelial OC (EOC), the most common form of OC, accounts for 90% of all OC cases \[2\]. EOC has the highest mortality among all gynecologic tumors and poses a serious threat to women's life \[3\].herefore, early clinical diagnosis is crucial. Commonly used laboratory indicators for OC diagnosis

Conditions

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Ovarian Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

\- patients at South Egypt Cancer institute and Recently diagnosed ovarian cancer patients 2. Patients not went to surgery.

Exclusion Criteria

* . Patients receive any anti-cancer therapy. 2. Patients diagnosed with other concomitante cancer or chronic disease

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Responsible Party

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Marwa Mamdouh Mohamed Abdellah

doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Marwa MamDouh Mohamed

Role: CONTACT

Phone: 20+1153538300

Email: [email protected]

Other Identifiers

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CircDENND4C in ovarian cancer

Identifier Type: -

Identifier Source: org_study_id