Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases

NCT ID: NCT05403216

Last Updated: 2025-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-01

Study Completion Date

2024-12-31

Brief Summary

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On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.

Detailed Description

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For oral lichen planus patients, the prevalence of Hashimoto's thyroiditis will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.

Besides, for patients with Hashimoto's thyroiditis, the prevalence of oral lichen planus will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.

Conditions

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Oral Lichen Planus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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OLP(-)

Oral lichen planus (OLP) with negative thyroid antibody group

No interventions assigned to this group

OLP(+)

OLP with positive thyroid antibody group

no intervention

Intervention Type OTHER

Interventions

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no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* OLP patients without systemic disease

Exclusion Criteria

* OLP patients with severe periodontal disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Dental Hospital of Zhejiang University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Qianming Chen

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Qianming Chen, Dr.

Role: STUDY_CHAIR

Zhejiang University

Locations

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The Stomatology Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

Site Status

Countries

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China

Other Identifiers

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I20210609

Identifier Type: -

Identifier Source: org_study_id

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