A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-09

Study Completion Date

2025-04-24

Brief Summary

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Due to the scarcity of data on prognostic and predictive influence on CCA, epidemiological studies evaluating these factors need to be developed in patients with CCA. Therefore, the investigators want to evaluate the profile of patients in the real world and from various parts of the world, describing prognostic factors such as CD4 dosage, time of HIV infection, evaluation of viral load, diagnosis of AIDS, geographic region of diagnosis and treatment, clinical staging, medications concomitant with QRT (risk of drug interactions), comorbidities (possible impact on dose-intensity), use of HAART, time of use of HAART, radiotherapy modality (conventional 3D vs Modulated Beam Intensity \[IMRT\], response to Nigro vs CTII regimens, as well as comparing clinical outcomes with patients without HIV infection.

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Detailed Description

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Conditions

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Anal Squamous Cell Carcinoma HIV Infections

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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With HIV Infection

Patients with CCA with HIV infection,

No interventions assigned to this group

Without HIV Infection

Patients with CCA without HIV infection,

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients 18 years of age or older
* Confirmed histological diagnosis of anal canal squamous cell carcinoma. Basaloid subtype is accepted
* Have underundered serological test for HIV infection
* Any clinical stage