Fistula-associated Anal Adenocarcinoma

NCT ID: NCT05381324

Last Updated: 2022-05-19

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 1004 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 1999-01-01
• Study Completion Date: 2022-05-01

Brief Summary

The fistula-associated anal adenocarcinoma is rare in patients suffering from anal fistulas. There is only little data available for this patient collective making characterization and management of this disease difficult. Late diagnosis and advanced tumor stage at diagnosis result in poor clinical outcome. It is the purpose of this study to evaluate patients clinically diagnosed with a FAAC and to further perform a histopathological characterization of the available tumor specimen.

Detailed Description

All patients receiving surgery for an anal fistula in the years 1999 to 2019 at a tertiary university referral hospital were included in the analysis. A retrospective review of patients' charts was performed. Patients suffering from FAAC were eligible for histopathological analysis including immunohistochemistry and molecular profiling.

Conditions

Rectal Cancer

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• anal fistula

Exclusion Criteria

• previous cancer of the anal canal

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Medical University of Vienna

OTHER

Sponsor Role: lead

Responsible Party

Felix Harpain

Dr.med.univ.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

1258

Identifier Type: -

Identifier Source: org_study_id