High Resolution Anuscopy Study

NCT ID: NCT06697964

Last Updated: 2025-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-08-08

Study Completion Date

2029-07-31

Brief Summary

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The majority of anal squamous cell carcinomas (SCC) stem from infection with high-risk human papillomavirus (HPV). Anal SCC is rare among the general population but affects several populations disproportionately.

High-risk groups are screened through anal swabs for anal cytology and detection of high risk human papillomavirus (HR HPV). HRA referral is recommended for individuals with abnormal cytology.

HRA represents the only method to identify precancerous lesions of the anal canal, with only few specialists knowledgeable about it.

At UZ Brussel, the investigators collected a wealth of data about HPV infection and its association with anal pathology. By establishing a comprehensive study, the investigators can delve into this data with specific research questions, conducting valuable research to provide answers to pressing clinical questions and contribute to advancements in medical understanding and treatment.

Detailed Description

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Conditions

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Human Papilloma Virus Anal Squamous Cell Carcinoma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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HRA

High resolution anoscopy to help evaluate anal conditions such as precancerous lesions

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All patients who have undergone HRA and all future patients referred for HRA in UZ Brussel
* 18 years or older
* Understands and able to speak and write in French, Dutch or English

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitair Ziekenhuis Brussel

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UZ Brussel

Jette, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Magali Surmont

Role: CONTACT

+32 2 477 ext. 60 11

Facility Contacts

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Magali Surmont

Role: primary

+32 2 477 ext. 60 11

Other Identifiers

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HRA Study

Identifier Type: -

Identifier Source: org_study_id

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