Phacoemulsification in Acute Congestive Glaucoma

NCT ID: NCT05289453

Last Updated: 2022-03-21

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 25 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-02-20
• Study Completion Date: 2022-06-20

Brief Summary

Acute primary angle closure (APAC) is usually caused by an abrupt closure of the trabecular meshwork in the anterior chamber angle that leads to a sudden rise in intraocular pressure (IOP). APAC is a subgroup of angle closure disease characterised by a sudden onset of headache, blurred vision, seeing halos around lights, corneal oedema, mid-dilated pupil, eye pain and redness. Asian also has a much higher incident rate of APAC compare to the Caucasian population - with the crude incidence rate of 12.2 and 10.4 per 100,000 people per year in the above 30-year-old population of Singapore and Hong Kong, respectively . This is higher than the average incidence rate of 3.9-4.1 cases per 100,000 people per year in the European regions .

In APAC, both LPI and primary lens extraction by phacoemulsification and intraocular lens implant (phaco/IOL) were demonstrated to be effective to control IOP elevation. The latter has been shown to be the more effective treatment than LPI for IOP reduction at the early and mid-term IOP control. Together with the advancement of phaco/IOL technique, primary lens extraction is the more popular choice of treatment nowadays. However, operating on an eye with early aborted APAC is technically challenging and may increase the risk of complications because of the presence of corneal oedema, inflammation, shallow anterior chamber, floppy iris and unstable lens. Furthermore, "the best time window" for performing lens extraction after an APAC attack remains uncertain. The long-term results (e.g. more than 5 years) of early lens extraction compared to the conventional LPI are also unknown. In this study, we summarise the approach of treating APAC at the initial acute stage and review the studies that consider IOP control in the mid and long term. We would also touch on the role of goniosynechialysis, trabeculectomy and endoscopic cyclophotocoagulation in treating APAC, as well as considering the economic aspect of treatment.

Aim of the study: to evaluate the safety and efficacy of phacoemulsificatiojn in cases of acute congestive glaucoma

Conditions

Glaucoma

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

study group

patients wit acute congestive glaucoma and treated bt lens extraction by phacoemulsification after IOP control

Group Type: EXPERIMENTAL

lens extraction by phacoemulsification

Intervention Type: PROCEDURE

lens extraction by phacoemulsification

Interventions

lens extraction by phacoemulsification

lens extraction by phacoemulsification

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• patients with acute congestive glaucoma

Exclusion Criteria

• people under 18 years

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hany Mahmoud

OTHER

Sponsor Role: lead

Responsible Party

Hany Mahmoud

principal investigator

Responsibility Role: SPONSOR_INVESTIGATOR

Locations

Hany Mahmoud

Sohag, , Egypt

Site Status: RECRUITING

Countries

Egypt

Facility Contacts

Hany Mahmoud, MD

Role: primary

drhanymahmoud@gmail.com

00201024368111

Other Identifiers

soh-med-22-02-29

Identifier Type: -

Identifier Source: org_study_id