Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients
NCT ID: NCT01136473
Last Updated: 2015-02-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
40 participants
OBSERVATIONAL
2011-07-31
2014-09-30
Brief Summary
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Detailed Description
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Lens epithelial cells will be isolated and will be used in a co-culture setup with trabecular cells to investigate the interactions between lens cells and trabecular cells. Understanding the interaction between young and adult lens cells on trabecular cell will shed light on mechanism of infantile aphakic glaucoma.
Aqueous humor taken out before cataract surgery and before glaucoma operation of aphakic eyes will be used for analysis of growth factor and cytokines in the Aphakic eye using proteins membrane arrays. Eyes before cataract surgery will be used as controls. Such analysis will shed light on the possible factors affecting trabecular cells in aphakic eye.
Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Study Groups
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congenital cataract or aphakic glaucoma
children with congenital cataract or aphakic glaucoma
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* children with aphakic or pseudophakic glaucoma and are going to do glaucoma surgery
* both of parents are able to sign the INFORMED CONSENT FORM
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Carmel Medical Center
OTHER
Responsible Party
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Orna Geyer
Professor
Principal Investigators
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Orna Geyer, Prof
Role: PRINCIPAL_INVESTIGATOR
Carmel Medical Center
Locations
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Carmel Medical Center
Haifa, , Israel
Countries
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Other Identifiers
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CMC-10-0035-CTIL
Identifier Type: -
Identifier Source: org_study_id
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