Clinical Observational Registry of Patients With Left Bundle Branch Block
NCT ID: NCT05283603
Last Updated: 2022-03-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
1000 participants
OBSERVATIONAL
2019-07-31
2029-07-31
Brief Summary
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Aims
1. To investigate the clinical, ECG, imaging-derived features in a large cohort of patients affected by LBBB on ECG.
2. To identify predictors of LBBB-induced LV systolic dysfunction and predictors of outcome in this population.
3. To derive data which may have an impact on therapeutic management.
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Interventions
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ECG, Echocardiogram, Magnetic resonance
Clinical and instrumental follow-up
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Previous cardiac surgery or transcatheter aortic valve implantation (TAVI)
* Congenital structural heart disease
* Patients implanted with permanent right ventricular stimulation devices and permanent pacing
* Denial to consent
18 Years
ALL
No
Sponsors
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Azienda Ospedaliero Universitaria di Sassari
OTHER
Responsible Party
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Giuseppe Damiano Sanna
MD PhD
Locations
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Cardiology, AOU Sassari
Sassari, , Italy
Countries
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Central Contacts
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Giuseppe D Sanna, MD PhD
Role: CONTACT
Facility Contacts
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References
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Sanna GD, De Bellis A, Zecchin M, Beccu E, Carta P, Moccia E, Canonico ME, Parodi G, Sinagra G, Merlo M. Prevalence, clinical and instrumental features of left bundle branch block-induced cardiomyopathy: the CLIMB registry. ESC Heart Fail. 2021 Dec;8(6):5589-5593. doi: 10.1002/ehf2.13568. Epub 2021 Sep 12.
Sanna GD, Merlo M, Moccia E, Fabris E, Masia SL, Finocchiaro G, Parodi G, Sinagra G. Left bundle branch block-induced cardiomyopathy: a diagnostic proposal for a poorly explored pathological entity. Int J Cardiol. 2020 Jan 15;299:199-205. doi: 10.1016/j.ijcard.2019.06.008. Epub 2019 Jun 4.
Moccia E, Sanna GD, Parodi G. Transient left bundle branch block and intraventricular dyssynchrony as a cause of reversible left ventricular dysfunction: The "in vivo" documentation of spontaneous electrical remodeling. Ann Noninvasive Electrocardiol. 2019 Nov;24(6):e12667. doi: 10.1111/anec.12667. Epub 2019 May 29.
Other Identifiers
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PG/2019/8862
Identifier Type: -
Identifier Source: org_study_id
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