REGIONAL ANALGESIA TECHNIQUES FOR EFFECTIVE RECOVERY TO CORONARY ARTERY BYPASS SURGERIES: A RETROSPECTİVE STUDY IN A SINGLE CENTER EXPERIENCE

NCT ID: NCT05282303

Last Updated: 2022-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

221 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-07-10

Study Completion Date

2021-01-20

Brief Summary

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Background Pain after cardiac surgery is both multifocal and multifactorial. Sternotomy, sternal retraction, internal mammary dissection, posterior rib dislocation or fracture, possible brachial plexus injury, and mediastinal and pleural drains contribute to pain experienced in the immediate postoperative period. Ineffective pain management can cause systemic and pulmonary complications and significant cardiac consequences.

Methods This study was conducted to compare the effectiveness of regional anesthesia techniques for perioperative pain management in cardiac surgery patients at our clinic. The effects of analgesic methods, in terms of contributing to recovery, have been examined.

Detailed Description

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This study was approved by the Koç University Clinical Research Ethics Committee (2021.464.IRB1.131); patients who underwent coronary artery bypass grafting (CABG) surgery at the VKV American Hospital between January 2015 and May 2020 were reviewed retrospectively. Patients with a history of cerebrovascular events, scheduled carotid surgery, or emergency CABG surgery were excluded from the study. Demographic data from the preoperative evaluation forms and operation types from the surgery reports were recorded. Intraoperative anesthesia follow-up forms were assessed if regional anesthesia was used, and the type and extent of opioids during the operation were examined. The postoperative transfer forms were examined to the cardiovascular intensive care unit (CICU), intensive care follow-up forms, and service ward record follow-up forms. Pain scores (NRS) during rest and coughing, vital signs, mobilization, and the start of respiratory exercises were recorded for postoperative respiratory complications.

Conditions

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Postoperative Pain

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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DIESPB

Dual injection of erector spinae plane block

CABG operation

Intervention Type PROCEDURE

Efficacy of regional analgesia techniques in coronary artery bypass operations

TPVB

Thoracic paravertebral block

CABG operation

Intervention Type PROCEDURE

Efficacy of regional analgesia techniques in coronary artery bypass operations

SAB

Serratus anterior plane block

CABG operation

Intervention Type PROCEDURE

Efficacy of regional analgesia techniques in coronary artery bypass operations

PIB

Parasternal ıntercostal block

CABG operation

Intervention Type PROCEDURE

Efficacy of regional analgesia techniques in coronary artery bypass operations

Interventions

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CABG operation

Efficacy of regional analgesia techniques in coronary artery bypass operations

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Who underwent coronary artery bypass grafting (CABG) surgery at the VKV American Hospital between January 2015 and May 2020 were reviewed retrospectively

Exclusion Criteria

* History of cerebrovascular event
* History of Alzheimer's and dementia
* Inadequate cognitive functions
* History of chronic pain
* Long-term opioid therapy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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V.K.V. American Hospital, Istanbul

OTHER

Sponsor Role lead

Responsible Party

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Sami Kaan Coşarcan

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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American Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Bigeleisen PE, Goehner N. Novel approaches in pain management in cardiac surgery. Curr Opin Anaesthesiol. 2015 Feb;28(1):89-94. doi: 10.1097/ACO.0000000000000147.

Reference Type RESULT
PMID: 25500688 (View on PubMed)

Doehring A, Oertel BG, Sittl R, Lotsch J. Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain. Pain. 2013 Jan;154(1):15-23. doi: 10.1016/j.pain.2012.06.011.

Reference Type RESULT
PMID: 23273101 (View on PubMed)

Nagaraja PS, Ragavendran S, Singh NG, Asai O, Bhavya G, Manjunath N, Rajesh K. Comparison of continuous thoracic epidural analgesia with bilateral erector spinae plane block for perioperative pain management in cardiac surgery. Ann Card Anaesth. 2018 Jul-Sep;21(3):323-327. doi: 10.4103/aca.ACA_16_18.

Reference Type RESULT
PMID: 30052229 (View on PubMed)

Engelman DT, Ben Ali W, Williams JB, Perrault LP, Reddy VS, Arora RC, Roselli EE, Khoynezhad A, Gerdisch M, Levy JH, Lobdell K, Fletcher N, Kirsch M, Nelson G, Engelman RM, Gregory AJ, Boyle EM. Guidelines for Perioperative Care in Cardiac Surgery: Enhanced Recovery After Surgery Society Recommendations. JAMA Surg. 2019 Aug 1;154(8):755-766. doi: 10.1001/jamasurg.2019.1153.

Reference Type RESULT
PMID: 31054241 (View on PubMed)

Elsharkawy H, Pawa A, Mariano ER. Interfascial Plane Blocks: Back to Basics. Reg Anesth Pain Med. 2018 May;43(4):341-346. doi: 10.1097/AAP.0000000000000750.

Reference Type RESULT
PMID: 29561295 (View on PubMed)

Other Identifiers

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Cosarcan3

Identifier Type: -

Identifier Source: org_study_id

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