AQP-1 Polymorphism on Fluid Status in Hemodialysis Patients

NCT ID: NCT05275387

Last Updated: 2022-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-01

Study Completion Date

2023-02-28

Brief Summary

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It is a cross sectional observational study. It is to investigate whether AQP-1 polymorphism has any impact on fluid status in hemodialysis patients. The long term stable HD patients in the current center will be enrolled to the study after informed consent. Blood samples will be collected for gene-typing. Fluid status including blood pressure, weekly UF and intra-dialysis body weight change will be collected through their clinical records.

Detailed Description

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Conditions

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End Stage Renal Disease on Dialysis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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observational study, no intervention

observational study, no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age 18-70
* ESRD
* maintained HD
* no target weight change during the last week of entering the study and achieve target weight at the end of HD section
* informed consented

Exclusion Criteria

* expected survival time less than 3 months
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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RenJi Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zanzhe Yu

Prinical Inverstigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zanzhe Yu, PhD

Role: PRINCIPAL_INVESTIGATOR

RenJi Hospital

Locations

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Renji Hospital

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Central Contacts

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Zanzhe Yu, PhD

Role: CONTACT

15901988349

Qi Lu, MD

Role: CONTACT

Other Identifiers

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KY2021-149-B

Identifier Type: -

Identifier Source: org_study_id

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