Influence of Different Toric Intraocular Lenses on IOL-capsular Complex
NCT ID: NCT05263518
Last Updated: 2022-04-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
100 participants
INTERVENTIONAL
2022-05-01
2022-12-01
Brief Summary
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Detailed Description
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Although up to 2-3 degree tilt and a 0.2-0.3 mm decentration are common and clinically unnoticed for any design of IOL, larger extent of tilt and decentration has a negative impact on the optical performance. IOL decentration ≥ 0.4 mm or/and IOL tilt ≥7degree were considered clinically significant because of poor post-surgery visual quality especially for optical sophisticated IOLs such as toric IOLs. IOL instability could decrease the curative effect of toric IOL. There are numerous types of toric IOLs; however, AcrySof IQ and TECNIS toric IOL are most frequently used in the Ophthalmology Hospital of Wenzhou Medical University. AcrySof IQ IOL has some differences compared with TECNIS toric IOL. IQ has a modified L haptic design while TECNIS® toric IOL has a modified C haptic design. AcrySof IQ IOL has a discontinuous 360˚ posterior square edge while TECNIS toric IOL has a continuous 360˚ posterior square edge. The AcrySof IQ IOL cylinder power models include 1.00, 1.50, 2.25, 3.00, 3.75, 4.50, 5.25 and 6.00 D. The Tecnis IOL cylinder power models include 1.00, 1.50, 2.25, 3.00 and 4.00 D. Previous study pointed that patients with cataracts with corneal astigmatism achieved comparable improvement in visual acuity, astigmatism correction, CS（sensitive contrast）, rotational stability and satisfaction, following AcrySof and TECNIS toric IOL implantation. However，some other studies found that the Acrysof toric IOL showed significantly greater rotational stability than the Tecnis toric IOL and the rate of surgical IOL repositioning was higher in eyes implanted with TECNIS than with AcrySof toric IOLs for astigmatic correction. Currently, there is no literature guidance to compare the results of cataract surgery combined various types of toric IOLs implantation in patients using CASIA2. The novel anterior segment optical coherence tomography (AS-OCT) device, CASIA2 can accurately evaluate the IOL capsule bending and the lens position after cataract surgery. Also, CASIA2 can be used to documented the dynamic changes of IOL-capsular complex after surgery.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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AcrySof IQ toric IOL
patients who had cataract surgery with AcrySof IQ toric IOL implantation. The patients diagnosed age related cataract The patients' ages are over 50.
Cataract surgery with AcrySof IQ IOL implantation.
Patients in this study will receive cataract surgery with AcrySof IQ IOL implantation.
TECNIS toric IOL
patients who had cataract surgery with TECNIS toric IOL implantation. The patients are diagnosed age related cataract. The patients' ages are over 50.
Cataract surgery with TECNIS toric IOL implantation.
Patients in this study will receive cataract surgery with TECNIS toric IOL implantation.
Interventions
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Cataract surgery with AcrySof IQ IOL implantation.
Patients in this study will receive cataract surgery with AcrySof IQ IOL implantation.
Cataract surgery with TECNIS toric IOL implantation.
Patients in this study will receive cataract surgery with TECNIS toric IOL implantation.
Eligibility Criteria
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Inclusion Criteria
* The patients' age over 50 years old
* The patients plan to receive cataract surgery in Eye hospital of Wenzhou Medical University
* The dilated pupils are over 7mm
* Patients are willing and able to complete the follow-ups.
Exclusion Criteria
* Patients have complications in the surgery and after surgery
* Patients have other severe diseases of eyes
50 Years
90 Years
ALL
No
Sponsors
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Wenzhou Medical University
OTHER
Responsible Party
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Yune Zhao
Vice president of Eye Hospital of Wenzhou Medical University
Principal Investigators
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Yune Zhao
Role: STUDY_DIRECTOR
Ophthalmology and Optometry Hospital
Central Contacts
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Yune Zhao, MD
Role: CONTACT
References
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Wang Y, Lou X, Qian S, Li Y, Wu X, Li S, Wang Y, Zhao Y, Chang P. Comparison of the effect of capsular bend on the rotational stability between 2 toric intraocular lenses. J Cataract Refract Surg. 2024 Mar 1;50(3):283-288. doi: 10.1097/j.jcrs.0000000000001373.
Other Identifiers
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TORIC stability
Identifier Type: -
Identifier Source: org_study_id
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