Clinical Evaluation of Toric Intraocular Lens

NCT ID: NCT03242486

Last Updated: 2018-02-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-12-31

Study Completion Date

2017-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Evaluate efficacy and safety of the toric IOL implanted into aphakic eye with corneal astigmatism after cataract surgery.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Effectiveness

* primary endpoint is visual acuity with pre-determined spherical correction.
* secondary endpoint is UCVA with spherical correction, BSCVA, Refractive Cylinder Correction, Spherical Equivalent, IOL rotation

Safety

* number and percentage of adverse event

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cataract Astigmatism

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

toric intraocular lens

toric intraocular lens is implanted to all subjects

Group Type EXPERIMENTAL

toric intraocular lens

Intervention Type DEVICE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

toric intraocular lens

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with age of 40 years or older
* Patients with age-related cataract in one eye or both eyes.
* Patients willing to participate in the required postoperative study.
* Patient who can understand and sign the consent document.
* An eye whose pupil diameter after mydriasis is 5 mm or greater.
* An eye whose preoperative corneal cylindrical power is 1.0D or more.
* An eye whose postoperative astigmatism is predicted to be less than 0.5 D.
* An eye whose postoperative visual acuity with spherical addition is 0.8 D or more.

Exclusion Criteria

* Disorder of corneal endothelium
* Uncontrolled glaucoma
* Active Uveitis
* Diabetic retinopathy
* Retinal detachment
* Congenital ocular anomalies
* Choroidal hemorrhage
* Shallow anterior chamber
* Microphthalmus
* Corneal dystrophy
* Optic atrophy
* Ocular hypertension
* Amblyopia
* Previous history of corneal transplantation
* Active Iritis
* Corneal disorder
* Macular degeneration
* Retinal degeneration
* Clinically significant change in macula and/or retinal pigment epithelium
* Corneal irregular astigmatism
* Atopic disease
* Brittleness of Zinn's zonule, fractured zonule and lens luxation (including subluxation)
* Pseudo-exfoliation syndrome
* Iris neovascularization
* Long axis length eye (axis length : 28mm or more)
* Severe dry eye, abnormality of the lens surface
* Concurrent participation in another drug and device clinical investigation
* Patient with mental deficiency or psychiatric disorder and/or who is not capable of expressing the consent of participating in the trial
* Patient who is judged inappropriate by investigators or sub-investigators
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Nidek Co. LTD.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

References

Explore related publications, articles, or registry entries linked to this study.

Sugita I, Ogawa T, Ichikawa K, Okita T, Negishi K, Nakano T, Tsuneoka H. Rotational stability and clinical outcomes of a new one piece toric intraocular lens with anchor-wing haptics. BMC Ophthalmol. 2022 Jan 15;22(1):26. doi: 10.1186/s12886-021-02240-7.

Reference Type DERIVED
PMID: 35033047 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

TIOL-YST

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.