A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)

NCT ID: NCT01045733

Last Updated: 2012-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-12-31

Study Completion Date

2011-05-31

Brief Summary

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The purpose of this study was to evaluate and compare postoperative corneal aberrations and visual parameters in patients contralaterally implanted with an AcrySof IQ Toric intraocular lens (IOL) and AcrySof IQ Aspheric IOL with concomitant limbal relaxing incision.

Detailed Description

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Conditions

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Cataract Astigmatism

Keywords

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Cataract Toric IOL AcrySof LRI Astigmatism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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IQ Toric IOL

AcrySof IQ Toric intraocular lens (IOL) randomly assigned to one eye, with AcrySof IQ Aspheric IOL with Limbal Relaxing Incision (LRI) procedure in the fellow eye for contralateral implantation.

Group Type EXPERIMENTAL

AcrySof IQ Toric IOL

Intervention Type DEVICE

AcrySof IQ Toric intraocular lens implanted in the capsular bag of the eye during cataract surgery. The IOL is intended for the lifetime of the patient.

IQ Aspheric IOL + LRI

AcrySof IQ Aspheric intraocular lens (IOL) with Limbal Relaxing Incision (LRI) procedure randomly assigned to one eye, with AcrySof IQ Toric IOL in the fellow eye for contralateral implantation

Group Type ACTIVE_COMPARATOR

AcrySof IQ Aspheric IOL

Intervention Type DEVICE

AcrySof IQ aspheric intraocular lens implanted in the capsular bag of the eye during cataract surgery. The IOL is intended for the lifetime of the patient.

Limbal Relaxing Incision (LRI)

Intervention Type PROCEDURE

An incision was made at the corneal-limbal junction during cataract surgery for the purpose of relaxing corneal curvature, ie., correcting astigmatism.

Interventions

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AcrySof IQ Toric IOL

AcrySof IQ Toric intraocular lens implanted in the capsular bag of the eye during cataract surgery. The IOL is intended for the lifetime of the patient.

Intervention Type DEVICE

AcrySof IQ Aspheric IOL

AcrySof IQ aspheric intraocular lens implanted in the capsular bag of the eye during cataract surgery. The IOL is intended for the lifetime of the patient.

Intervention Type DEVICE

Limbal Relaxing Incision (LRI)

An incision was made at the corneal-limbal junction during cataract surgery for the purpose of relaxing corneal curvature, ie., correcting astigmatism.

Intervention Type PROCEDURE

Other Intervention Names

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AcrySof IQ Toric IOL Model SN6AT3 AcrySof IQ Toric IOL Model SN6AT4 AcrySof IQ Toric IOL Model SN6AT5 AcrySof IQ Aspheric IOL Model SN60WF

Eligibility Criteria

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Inclusion Criteria

Ocular criteria must be met in both eyes.

* Willing and able to understand and sign an informed consent;
* Willing and able to attend postoperative examinations per protocol schedule;
* Have cataracts that require extraction followed by implantation of a posterior chamber intraocular lens and used as an on-label procedure;
* Free of disease(s)/condition(s) listed in the "Caution" section of the AcrySof IQ and AcrySof IQ Toric package inserts;
* Have regular, bowtie shaped corneal astigmatism and qualify for an SN6AT3, SN6AT4 or SN6AT5 Intraocular Lens (IOL) in both eyes;
* Have the second surgery at least one week following the first eye implant but not later than one month after the first implant.

Exclusion Criteria

* Previous corneal surgery;
* Planned multiple procedures during cataract/IOL implantation surgery;
* Ocular disease and/or condition that may compromise study results;
* Pregnant or planning pregnancy during course of study;
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Contact Alcon Call Center for Trial Locations

Fort Worth, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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M-09-045

Identifier Type: -

Identifier Source: org_study_id