Evaluation of Gas Propagation in Snow During Breathing of Subjects Under Simulated Avalanche Snow

NCT ID: NCT05262894

Last Updated: 2022-03-02

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-02-07
• Study Completion Date: 2025-05-31

Brief Summary

The study is aimed at investigation of respiratory gases propagation in snow. The study involves volunteers breathing into the snow whereas concentrations of gases are measured at various positions in the snow.

Detailed Description

The study is aimed at investigation of respiratory gases (oxygen and carbon dioxide) propagation in the simulated avalanche snow. The study involves volunteers breathing into the snow whereas concentrations of gases are measured at various positions in the snow. A special apparatus was created for sampling and measurement of gas concentrations and to assure stable geometry of the experiment required for data evaluation.

Conditions

Accident Caused by Snow Avalanche

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Breathing in the snow

Breathing in the snow using a specially designed apparatus and measuring the respiratory gases distribution in snow.

Group Type: EXPERIMENTAL

extreme hypercapnia induced by ventilation insufficiency

Intervention Type: OTHER

Re-breathing of gas by breathing into the simulated avalanche snow

Interventions

extreme hypercapnia induced by ventilation insufficiency

Re-breathing of gas by breathing into the simulated avalanche snow

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• healthy and fit volunteers, classified as The American Society of Anesthesiologists class I
• without a smoking history

Exclusion Criteria

• Tiffeneau Index less than 0.70
• any cardiovascular or respiratory condition

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Czech Technical University in Prague

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Karel Roubik, prof.

Role: PRINCIPAL_INVESTIGATOR

Czech Technical University in Prague, Fac. of Biomedical Engineering

Locations

Czech Technical University, Faculty of Biomedical Engineering

Kladno, , Czechia

Countries

Czechia

References

Roubik K, Sieger L, Sykora K. Work of Breathing into Snow in the Presence versus Absence of an Artificial Air Pocket Affects Hypoxia and Hypercapnia of a Victim Covered with Avalanche Snow: A Randomized Double Blind Crossover Study. PLoS One. 2015 Dec 14;10(12):e0144332. doi: 10.1371/journal.pone.0144332. eCollection 2015.

Reference Type: BACKGROUND

PMID: 26666523 (View on PubMed)

Roubik K, Sykora K, Sieger L, Ort V, Horakova L, Walzel S. Perlite is a suitable model material for experiments investigating breathing in high density snow. Sci Rep. 2022 Feb 8;12(1):2070. doi: 10.1038/s41598-022-06015-y.

Reference Type: BACKGROUND

PMID: 35136116 (View on PubMed)

Other Identifiers

2022-Bradler

Identifier Type: -

Identifier Source: org_study_id