LFR-260 vs Traditional Phoropter in Visual Acuity Testing

NCT ID: NCT05259163

Last Updated: 2024-09-25

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

112 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-06-07

Study Completion Date

2023-01-06

Brief Summary

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The purpose of this study is to establish if LFR-260 (investigational device) is not inferior in effectiveness to a traditional phoropter (control device) when applied in visual acuity test in subjects undergoing a full routine eye examination. LFR-260 proposes to provide information of the visual capabilities of the patient. The test will be provided and supervised by a qualified eye care provider. The informed consent, screening, randomization (into the order of visual test device used), (visual) device testing (to include precision testing, remote and offsite testing) will all occur at a single visit.

Detailed Description

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Conditions

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Visual Acuity Astigmatism Anisometropia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

The investigational product was compared to the traditional phoropter. Subjects were randomized to the order of testing.
Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Group 1: LFR-260 first, then traditional phoropter

The LFR-260 was administered first in this group, followed by the traditional phoropter. The LFR-260 is a portable digital refractor which allows for determination of refractive error as well as for fully remote refractions during eye exams. The traditional phoropter is intended to be used for distance vision testing in any environment.

Group Type EXPERIMENTAL

LFR-260 portable phoropter

Intervention Type DEVICE

Portable unit to evaluate visual refractive state of the patient

Traditional phoropter (SOC)

Intervention Type DEVICE

Standard unit for evaluating visual refractive state of the patient

Group II: Traditional Phoropter first, then LFR-260

The traditional phoropter was administered first in this group, followed by the traditional phoropter. The traditional phoropter is intended to be used for distance vision testing in any environment. The LFR-260 is a portable digital refractor which allows for determination of refractive error as well as for fully remote refractions during eye exams.

Group Type ACTIVE_COMPARATOR

LFR-260 portable phoropter

Intervention Type DEVICE

Portable unit to evaluate visual refractive state of the patient

Traditional phoropter (SOC)

Intervention Type DEVICE

Standard unit for evaluating visual refractive state of the patient

Interventions

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LFR-260 portable phoropter

Portable unit to evaluate visual refractive state of the patient

Intervention Type DEVICE

Traditional phoropter (SOC)

Standard unit for evaluating visual refractive state of the patient

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. The participant or legal guardian is willing and able to understand, sign and date the Ethics committee approved study specific Informed Consent Form.
2. The participant is a male or female between the ages of 12 and 65 (inclusive).
3. The participant has no more than mild to moderate far-sightedness, near-sightedness, astigmatism or anisometropia.
4. The participant is free of ocular and systemic abnormalities that might affect visual functions.

Exclusion Criteria

1. The participant has diabetes mellitus (Type 1 or 2).
2. The participant has an autoimmune condition.
3. The participant is pregnant (self-reported).
4. The participant has an active corneal or conjunctival infection.
5. The participant has an active corneal, conjunctival, or intraocular inflammation (i.e. - uveitis).
6. The participant has diabetic retinopathy.
7. The participant has glaucoma or ocular hypertension.
8. The participant has macular degeneration.
9. The participant has had a previous ocular surgery.
10. The participant has ocular and systemic diseases or abnormalities that might affect visual functions.
11. The participant has a history of amblyopia, strabismus, or any other binocular vision abnormality.
12. The participant has a history of AMD (age macular degeneration).
13. The participant is a prisoner, a transient or has been treated for alcohol and/or drug abuse in an inpatient substance abuse program within 6 months prior to proposed study enrolment.
14. The participant will not be able to complete questionnaires.
15. The participant is currently in an investigational study for a similar purpose.
16. The participant, in the judgment of the Investigator, may be inappropriate for the intended study procedures.
Minimum Eligible Age

12 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Evolution Optiks Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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MCPHS

Worcester, Massachusetts, United States

Site Status

Gold Coast Optometric Vision

Oyster Bay, New York, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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LFR-260-2021

Identifier Type: -

Identifier Source: org_study_id

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