The Utility of the Validated Intraoperative Bleeding Scale in Spine Surgery

NCT ID: NCT05258487

Last Updated: 2024-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

121 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-01

Study Completion Date

2023-03-14

Brief Summary

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This is a single-center, prospective, observational study that will compare the blood transfusion rate between intraoperative bleeding severity characterized using the Validated Intraoperative Bleeding Scale (VIBe).

Detailed Description

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Primary Aim: Assess the association between the VIBe scale and intraoperative and postoperative blood transfusion rates for posterior thoracolumbar spine surgery.

Primary Hypothesis: Patients with higher recorded VIBe grades during the five stages of spine surgery (exposure, decompression, instrumentation, fusion, and closing) will have a higher rate of receiving blood transfusions.

Secondary Aims: Determine the association between the VIBe scale and other postoperative outcomes and complications.

Conditions

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Intraoperative Blood Loss Thoracolumbar Spine Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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VIBe Grade 1

Intraoperative bleeding of grade 1 as defined by the VIBe scale.

No interventions assigned to this group

VIBe Grade 2

Intraoperative bleeding of grade 2 as defined by the VIBe scale.

No interventions assigned to this group

VIBe Grade 3

Intraoperative bleeding of grade 3 as defined by the VIBe scale.

No interventions assigned to this group

VIBe Grade 4

Intraoperative bleeding of grade 4 as defined by the VIBe scale.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Ages 18 to 88 years
* Patients receiving elective open, posterior thoracolumbar surgery

Exclusion Criteria

* Patients receiving non-elective or trauma surgery
* Patients with pathologic spine fracture or metastatic disease to the spine
* Patients receiving thoracolumbar surgery through anterior or lateral approach
* Patients receiving spine surgery for debridement of suspected or confirmed infection
Minimum Eligible Age

18 Years

Maximum Eligible Age

88 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Baxter Healthcare Corporation

INDUSTRY

Sponsor Role collaborator

University of Maryland, Baltimore

OTHER

Sponsor Role lead

Responsible Party

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Steven Ludwig

Chief of Spine Surgery, Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Steven C Ludwig, MD

Role: PRINCIPAL_INVESTIGATOR

University of Maryland, Baltimore

Locations

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University of Maryland Medical Center

Baltimore, Maryland, United States

Site Status

Countries

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United States

References

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Lewis KM, Li Q, Jones DS, Corrales JD, Du H, Spiess PE, Lo Menzo E, DeAnda A Jr. Development and validation of an intraoperative bleeding severity scale for use in clinical studies of hemostatic agents. Surgery. 2017 Mar;161(3):771-781. doi: 10.1016/j.surg.2016.09.022. Epub 2016 Nov 10.

Reference Type BACKGROUND
PMID: 27839931 (View on PubMed)

Other Identifiers

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HP-00097392

Identifier Type: -

Identifier Source: org_study_id

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