Muscle Strength and Total Knee Replacement

NCT ID: NCT05248815

Last Updated: 2025-05-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

57 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-12

Study Completion Date

2023-12-01

Brief Summary

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Purposes: To compare knee extensor muscle strength, physical function and self-reported function before and after total knee replacement with healthy age-matched controls. To describe changes in knee extensor muscle strength up to one year after surgery. To study the relationship between changes in knee extensor muscle strength and changes in physical function, self-reported function and physical activity level and the relationship between changes in knee extensor muscle strength and satisfaction.

Methods: A prospective observational study and comparison with controls. 50-55 individuals aged 65 or older, scheduled for total knee arthroplasty will be recruited to the study group. Measurement of study group 0-2 weeks before surgery and 3, 6 and 12 months following surgery. Comparison with 50-55 healthy age-matched controls.

Detailed Description

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Conditions

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Arthropathy of Knee Osteo Arthritis Knee

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Study group

Patients scheduled for total knee replacement.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Scheduled for total knee replacement on the basis of osteoarthritis of the knee
* Expected rehabilitation in a primary care setting

Exclusion Criteria

* Difficulties reading or speaking Swedish
* Revision surgery
* Rehabilitation in other settings than primary care
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Vastra Gotaland Region

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anette Larsson, PhD

Role: PRINCIPAL_INVESTIGATOR

Närhälsan Rehabilitering

Locations

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Närhälsan Sörhaga Rehabmottagning

Alingsås, , Sweden

Site Status

Närhälsan Herrljunga Rehabmottagning

Herrljunga, , Sweden

Site Status

Närhälsan Lerum Rehabmottagning

Lerum, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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Muscle strength and TKP

Identifier Type: -

Identifier Source: org_study_id

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