Return to Activity After Total Knee Arthroplasty

NCT ID: NCT07006545

Last Updated: 2025-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-01

Study Completion Date

2027-07-31

Brief Summary

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This multicenter research project aims to correlate objective testing of muscle mass, muscle strength, neuromuscular activation, walking speed and other functional tests with everyday activity and subjective quality of life after total knee arthroplasty. For this purpose, 400 patients from 5 orthopedic departments in Germany and USA will be examined at the time points pre-op, six weeks, three, six and 12 months post-op.

Detailed Description

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Conditions

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Total Knee Arthroplasty

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Total Knee Arthroplasty

Patients receiving a total knee arthroplasty

Return to Activity Battery

Intervention Type OTHER

The main target parameters are muscle mass (sonography), muscle strength (isometric maximum strength measurement), neuromuscular activation (surface EMG), functionality (e.g. 6MWT, chair rising test), knee swelling and subjective assessment of everyday and leisure activities, quality of life (e.g. SF-36) and return to work

Interventions

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Return to Activity Battery

The main target parameters are muscle mass (sonography), muscle strength (isometric maximum strength measurement), neuromuscular activation (surface EMG), functionality (e.g. 6MWT, chair rising test), knee swelling and subjective assessment of everyday and leisure activities, quality of life (e.g. SF-36) and return to work

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients receiving a total knee arthroplasty
* Ability to perform the return to activity battery

Exclusion Criteria

* Inability to perform the return to activity battery
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Bonn

OTHER

Sponsor Role lead

Responsible Party

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Alexander Franz

Dr. med., B.Sc.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Technical University Munich

Munich, Bavaria, Germany

Site Status

University Hospital Bonn

Bonn, North Rhine-Westphalia, Germany

Site Status

Countries

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Germany

Other Identifiers

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2024_I

Identifier Type: -

Identifier Source: org_study_id

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