Identifying Risks of COVID-19 Outbreaks in Work Settings and the Implications for Control Measures

NCT ID: NCT05197673

Last Updated: 2024-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

310 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-15

Study Completion Date

2023-05-30

Brief Summary

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Objectives: To identify core and cross-time workplace hazards and worker's exposure prevention profile towards outbreaks in three non-healthcare work settings; to evaluate effectiveness of a theory-based educational programme on improving attitude to vaccination and virus testing in workplace; to longitudinally compare attitude of willingness to vaccination, testing of SARS-CoV-2 and changes of risk profile toward outbreaks among workers.

Design: A 5-year study comprising a randomized controlled trial (RCT) and 3 parallel longitudinal studies with baseline and follow-up repeated measurements.

Setting: Non-office, mobile and office work settings. Participants: Part I is a RCT, 294 workers will be randomised to an intervention group (a theory-based education programme) and a control group with measurements repeated at 3rd, 6th and 9th month. Part II is a longitudinal quantitative study (i.e., prospective cohort study) involving 1,495 workers recruited at the baseline and followed up for 2 years. Part III is a longitudinal qualitative study involving 26 management and frontline workers. Part IV is a longitudinal workplace hygiene study involving 6 workplaces enrolled at the baseline and followed up to conduct ventilation investigation.

Intervention: Theory-based education intervention to build positive attitude of control measures towards SARS-CoV-2 outbreak.

Main outcome measure: Workplace hygiene data (airflow, air volume, etc.); willingness to vaccination and virus tests; actual uptake of SARS-CoV-2 antibody testing.

Data analyses: Multivariate regression logistic model and thematically analysed will be performed for quantitative and qualitative analysis. Intention-to-treat analysis will be employed for RCT.

Expected results: Large dataset of longitudinal measurement of willingness to vaccination/testing and actual uptake will be documented to inform policy. Educational intervention will be developed to mitigate risks of outbreaks in workplace.

Detailed Description

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Conditions

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Intention to Get SARS-CoV-2 Vaccination Intention to Get SARS-CoV-2 Antibody Test

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Intervention group will receive theory-based educational intervention using the Theory of Planned Behaviours (TPB) PLUS general health information; Control group will receive only general health information.
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Intervention group

This arm will receive TPB intervention to build positive attitudes towards COVID-19 related preventive behaviour (e.g., good compliance with infection control measures, encouraging uptake of testing and vaccination), subjective norms (tackling strategies for perceived social pressure from others or normative beliefs), and improve perceived behavioural control towards risks of outbreaks in workplace.

Group Type EXPERIMENTAL

Theory of planned behaviours (TPB) based intervention

Intervention Type BEHAVIORAL

Intervention group will receive TPB-based education program to improve workers' attitude toward SARS-CoV-2 and raise their intention to vaccination and virus testing. The intervention will be implemented at the baseline with measurements repeated at the 3rd month, 6th month and 9th month. The standardized mode of intervention includes face-to-face/online seminar (depends on the COVID-19 situation), message via mobile phone, promotion pamphlet, etc.

Control group

Control group will receive only general health information.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Theory of planned behaviours (TPB) based intervention

Intervention group will receive TPB-based education program to improve workers' attitude toward SARS-CoV-2 and raise their intention to vaccination and virus testing. The intervention will be implemented at the baseline with measurements repeated at the 3rd month, 6th month and 9th month. The standardized mode of intervention includes face-to-face/online seminar (depends on the COVID-19 situation), message via mobile phone, promotion pamphlet, etc.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* currently being employed in Hong Kong

Exclusion Criteria

* who have history of physician-diagnosed cancer and sever chronic diseases
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Tse Lap Ah

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lap Ah Tse

Role: PRINCIPAL_INVESTIGATOR

Chinese University of Hong Kong

Locations

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The Chinese University of Hong Kong

Shatin, New Territories, Hong Kong

Site Status

Countries

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Hong Kong

References

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Tse LA, Wang F, Mo PKH, Wan CCM, Tang NHY, Yang S, Dong D, Ho KF, Wong SY. Does enhanced educational intervention reduce breakthrough infection and mental health problems via improving acceptance of COVID-19 booster shots in Chinese non-healthcare workers: A randomized controlled trial? J Infect Public Health. 2025 May;18(5):102719. doi: 10.1016/j.jiph.2025.102719. Epub 2025 Feb 21.

Reference Type DERIVED
PMID: 40056893 (View on PubMed)

Constantin AM, Noertjojo K, Sommer I, Pizarro AB, Persad E, Durao S, Nussbaumer-Streit B, McElvenny DM, Rhodes S, Martin C, Sampson O, Jorgensen KJ, Bruschettini M. Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings. Cochrane Database Syst Rev. 2024 Apr 10;4(4):CD015112. doi: 10.1002/14651858.CD015112.pub3.

Reference Type DERIVED
PMID: 38597249 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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2021.531-T

Identifier Type: -

Identifier Source: org_study_id

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