Correlation Between Elastic Modulus of Ultrasonic Shear Wave and Tumor Stromal Component in Pancreatic Cancer

NCT ID: NCT05187416

Last Updated: 2022-01-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-01

Study Completion Date

2022-10-01

Brief Summary

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Pancreatic cancer is a gastrointestinal tumor with a high degree of malignancy. Currently, there are many first-line chemotherapy regimens in clinical practice, but the individual selection of chemotherapy regimens has not been unanimously recognized.This study is aimed at exploring the correlation between the two-dimensional shear wave elastography (2D - SWE) parameters and pancreatic cancer stromal elements proportion through an ultrasound scan for resectable pancreatic cancer cases and postoperative pathological specimen analysis. Then determine if the pancreatic cancer two-dimensional shear wave elastography can guide clinicians selecting chemotherapy scheme by predicting tumor stromal elements .These results are expected to provide an effective non-invasive diagnostic basis for individualized treatment of pancreatic cancer.

Detailed Description

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Conditions

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Pancreatic Neoplasms

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Interventions

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two-dimensional shear wave elastography

Preoperative ultrasound elastography examination

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

1. Patients with resectable pancreatic cancer underwent ultrasound examination before surgery
2. Conventional ultrasound can clearly show pancreatic space-occupying lesions and the elastic measurements show good images
3. The patient agrees to receive ultrasound elasticity examination and signs informed consent
4. All patients had no history of radiotherapy or chemotherapy before ultrasound examination
5. All clinical case data and auxiliary examination data are complete and accessible.

Exclusion Criteria

1. Ultrasound evaluation was not performed before ultrasound-guided needle biopsy
2. Conventional ultrasound could not clearly show pancreatic space-occupying lesions or poor elastic measurement images
3. Patients who refuse to accept examination or give up treatment
4. Patients receiving neoadjuvant chemotherapy or radiotherapy before ultrasound examination
5. Incomplete clinical data and auxiliary examination data.
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xijing Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Xijing Hospital

Xi'an, Shaanxi, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Kunlong Duan

Role: CONTACT

+8617795629885

Facility Contacts

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Ming Yu

Role: primary

+8613991181250

Other Identifiers

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KY20212175-C-1

Identifier Type: -

Identifier Source: org_study_id

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