Clevidipine in Neurocritical Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

33 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2019-09-01

Brief Summary

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Acute blood pressure elevation is a frequent problem in neurocritical patients. Its effective management is challenging and must avoid significant decreases of blood pressure leading to lower cerebral perfusion pressure worsening ischemia and elevations probably associated with bleeding, rebleeding or hematoma expansion associated with poor prognosis

Detailed Description

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Retrospective, observational and single-group study for observe effectiveness and safety of clevidipine for perioperative control of hypertension in patients admitted to Post-Operative Intensive Care Unit after thrombectomy for stroke, intracerebral hemorrhage requiring surgical treatment, embolization of aneurysm after subarachnoid hemorrhage, scheduled neurosurgical and neuroradiology procedures.

Conditions

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High Blood Pressure

Keywords

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clevidipine neurocritical

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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Clevidipine 0.5 MG/ML Intravenous Emulsion

Effectiveness and safety of clevidipine

Intervention Type DRUG

Other Intervention Names

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CLEVIPREX

Eligibility Criteria

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Inclusion Criteria

1. -Adult patients older than 18 years old admitted to Post-Operative Intensive Care Unit with neurocritical condition requiring surgical or interventional treatment.
2. -Acute High Blood Pressure requiring urgent treatment (SBP ≥160 mmHg or ≥ 20% increase in preoperative values that persists for more than 15 minutes)
3. -Clevidipine used as a first line or after failure of different antihypertensive drugs.

Exclusion Criteria

1. -Adults older than 90 years admitted to Post-Operative Intensive Care Unit with neurocritical condition requiring surgical or interventional treatment.
2. -Patients admitted to Post-Operative Intensive Care Unit with neurocritical condition not requiring surgical or interventional treatment.

Eligible Sex

Accepts Healthy Volunteers

No

Responsible Party

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Blanca Escontrela

Consultant Anesthesiology and Reanimation

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Blanca Escontrela, Consultant

Role: PRINCIPAL_INVESTIGATOR

Biocruces Bizkaia Health Research Institute

Locations

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Biocruces

Barakaldo, Vizcaya, Spain

Site Status

Countries

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Spain

Other Identifiers

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CEIC E19/17

Identifier Type: -

Identifier Source: org_study_id