Correlation Between Altered Glycometabolic Status and Joint Inflammation in Diabetic Patients With Osteoarthritis Undergoing Knee Arthroplasty

NCT ID: NCT05150119

Last Updated: 2022-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-15

Study Completion Date

2024-11-15

Brief Summary

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Evaluate the correlation between altered glycometabolic status and joint inflammation in diabetic patients with osteoarthritis undergoing knee replacement surgery

Detailed Description

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Conditions

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To Evaluate a Linear Positive Correlation Between Plasma HbA1c and Synovial IL-6 in Diabetic Patients

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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Evaluation of Synovial IL-6 in diabetic patients with gonarthrosis

To evaluate if there is a linear positive correlation between plasma glycated hemoglobin concentration HbA1c and synovial IL-6 in diabetic patients

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Evaluation of plasmatic HbA1c in diabetic patients with gonarthrosis

Eligibility Criteria

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Inclusion Criteria

* Diabetic patients
* Patients with osteoarthritis awaiting knee replacement surgery
* Patients awaiting knee replacement surgery
* Patients who agree to sign informed consent

Exclusion Criteria

* Patients less than 55 years of age.
* Patients over 85 years of age.
* Patients who are unable to understand and want.
* Patients with severe neurological disorders or with severe disabilities.
* Rheumatoid arthritis patients
* Cancer patients
* Patients suffering from chronic inflammatory bowel syndromes (RCU and Crohn's disease)
* Patients on immunosuppressive therapy
Minimum Eligible Age

55 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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IRCCS Istituto Ortopedico Galeazzi

Milan, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Cesare Donarini

Role: CONTACT

0248785220

Facility Contacts

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Cesare Donarini

Role: primary

0248785220

Other Identifiers

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GLICO PG

Identifier Type: -

Identifier Source: org_study_id

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