Chronic Knee Pain Study

NCT ID: NCT00776932

Last Updated: 2015-05-27

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 852 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2007-06-30
• Study Completion Date: 2013-06-30

Brief Summary

Specific Aims: 1) To examine differences between AA and white patients with knee OA in willingness to consider knee joint replacement. 2) To examine the relationship between socio-cultural factors and patient willingness to consider joint replacement. 3) To examine how demographic, socio-cultural, and clinical factors mediate the relationship between race and patient willingness. 4) To examine the relationship between patient willingness and referral to orthopedic care for knee OA (secondary aim).

Experimental design/Methodology: A cross-sectional survey study design will be used to examine socio-cultural and clinical factors that may vary by race/ethnicity and may be determinants of willingness to consider joint replacement as a treatment option. Patients with symptomatic and radiographic knee OA from the primary care clinics will be surveyed. Only individuals with knee OA of sufficient severity that would be considered candidates for joint replacement will be included. Analytic strategies include ordinal logistic regression, path analysis, and regression trees.

Subject population: The study sample will consist of approximately 133 African American and 419 white patients with OA of the knee in a primary care setting.

Conditions

Knee Osteoarthritis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Knee OA

Those over the age of 50 who have frequent pain in their knee that has lasted for at least six months.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• over age 50
• chronic knee pain
• radiographic evidence of knee OA

Exclusion Criteria

• previous joint replacement
• inflammatory arthritis

• Minimum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

National Institutes of Health (NIH)

NIH

Sponsor Role: collaborator

University of Pittsburgh

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

C. Kent Kwoh, MD

Role: PRINCIPAL_INVESTIGATOR

University of Pittsburgh

Locations

University of Pittsburh Arthritis Research Center

Pittsburgh, Pennsylvania, United States

Countries

United States

Other Identifiers

1 P60 AR05473-01

Identifier Type: -

Identifier Source: secondary_id

07040263

Identifier Type: -

Identifier Source: org_study_id