An Automatically Adjusting Prosthetic Socket for People With Transtibial Amputation

NCT ID: NCT05124652

Last Updated: 2022-09-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-18

Study Completion Date

2027-06-30

Brief Summary

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People with leg amputations often experience daily changes in the size (volume) of their residual limb. These daily changes can cause a prosthesis to fit poorly. They can also cause limb problems like pain or skin breakdown. Prosthetic socket systems that accommodate limb volume changes can help address these issues, but they require users to make adjustments throughout the day. The aim of this research is to create a system that will automatically adjust the fit of the socket and create a well-fitting prosthesis for people with leg amputations who experience volume fluctuations when using their prosthesis.

Detailed Description

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Conditions

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Lower Limb Amputation Below Knee (Injury) Diurnal Residual Limb Fluid Volume Fluctuation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

All aims will be conducted as randomized control trials and test various developments to the auto adjusting system, with each previous aim informing the next.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Focus Group Testing

Focus group testing of key-fob device to control adjusting socket system

Group Type NO_INTERVENTION

No interventions assigned to this group

In-Lab, Crossover Study

Testing of auto-adjusting algorithm in-lab. Participants will carry out a structured protocol wearing the socket in all modes. Order will be randomly assigned.

Group Type EXPERIMENTAL

Auto Adjusting Prosthesis

Intervention Type DEVICE

Participants will test the auto adjusting prosthesis. The prosthesis will be able to move up to 3 panels built into the socket walls to expand or tighten the socket's fit. The auto adjustments will take place during periods of sitting, standing, or walking. Manual adjustments will also be possible either via the researcher controlling the prosthesis or via the key fob developed in the first aim.

Out-of-Lab Crossover Study

Evaluate socket performance in user free-living environments. Participants will use the prosthesis in all modes by end of study, order will be randomly assigned.

Group Type EXPERIMENTAL

Auto Adjusting Prosthesis

Intervention Type DEVICE

Participants will test the auto adjusting prosthesis. The prosthesis will be able to move up to 3 panels built into the socket walls to expand or tighten the socket's fit. The auto adjustments will take place during periods of sitting, standing, or walking. Manual adjustments will also be possible either via the researcher controlling the prosthesis or via the key fob developed in the first aim.

Interventions

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Auto Adjusting Prosthesis

Participants will test the auto adjusting prosthesis. The prosthesis will be able to move up to 3 panels built into the socket walls to expand or tighten the socket's fit. The auto adjustments will take place during periods of sitting, standing, or walking. Manual adjustments will also be possible either via the researcher controlling the prosthesis or via the key fob developed in the first aim.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 18 or older (Prosthetists and Prosthesis Users)
* must have certification and regularly treat patients with trans-tibial limb loss in a clinical setting (Prosthetists only)
* had a trans-tibial amputation at least 12 months prior (prosthesis users only)
* regularly use a definitive prosthesis with pin lock suspension and few or no pads (prosthesis users only)
* self-report experiencing limb volume fluctuation in the past (prosthesis users only)
* have residual limb length of at least 9 cm (prosthesis users, Aim 2 and Aim 3 only)
* walk at least 5 continuous minutes and intermittently at least 1 hour (prosthesis users, Aim 2 and Aim 3 only)
* capable of distinguishing socket sizes too large and too small to be tolerated (Prosthetists and Prosthesis Users)

Exclusion Criteria

* Are not certified prosthetists (prosthetists only)
* neuropathy (prosthesis users only)
* reduced skin sensation (prosthesis users only)
* regular use of an assisted device (prosthesis users only)
* sores or skin breakdown on their residual limb (prosthesis users, Aim 2 and Aim 3 only)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

Sponsor Role collaborator

University of Washington

OTHER

Sponsor Role lead

Responsible Party

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Joan Sanders

Professor: Engineering

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Joan E Sanders, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Washington

Locations

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William H. Foege Hall

Seattle, Washington, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Katheryn Allen, CPO

Role: CONTACT

206-390-0228

Daniel Ballesteros

Role: CONTACT

Facility Contacts

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Katheryn Allyn

Role: primary

206-390-0228

Other Identifiers

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1R01HD103815-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

STUDY00009418

Identifier Type: -

Identifier Source: org_study_id

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