Noradrenergic Activity and Attention

NCT ID: NCT05120713

Last Updated: 2024-09-19

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

140 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-01

Study Completion Date

2023-11-20

Brief Summary

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Older adults demonstrate increased distractibility by task-irrelevant information which contributes to general cognitive impairment. However, it is yet unclear how changes in noradrenergic activity during aging influences attentional control. In the current study, tonic noradrenergic activity will be increased or decreased to investigate its behavioral and neural effects on attentional control.

Detailed Description

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Conditions

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Aging

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Young Adults

Young Adults aged 18-35

No interventions assigned to this group

Older Adults

Older Adults aged 50-80

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Fluent in English
* Aged between 18-35 or 50-80
* Have normal or corrected-to-normal vision and hearing, and normal color vision
* Have a mobile phone and email address

Exclusion Criteria

* Non-English speakers
* Currently practicing any relaxation, meditation, or breathing technique for more than an hour per week
* Have participated in studies measuring attentional capture in the past year
* Experiencing symptoms of dementia
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Southern California

OTHER

Sponsor Role lead

Responsible Party

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Mara Mather

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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USC Leonard Davis School of Gerontology

Los Angeles, California, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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UP-21-00711

Identifier Type: -

Identifier Source: org_study_id

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