CArdioMetabolism and Atherosclerotic PlaqUe progreSsion

NCT ID: NCT05117424

Last Updated: 2024-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Systematic metabolic diseases are closely related to prevalence and progression of atherosclerosis. This prospective cohort consecutively enrolls patients with coronary artery disease compliacted with metabolic abnormalities such as diabtetes, prediabetes, obesity, chronic kidney disease and hyperuricemia.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

CArdioMetabolism and Atherosclerotic PlaqUe progreSsion (CAMPUS) study is a single center, prospective cohort study to investigate the impact of cardiometabolic factors on coronary diseases. This study consecutively enrolls patients with coronary artery diseases complicatied with metabolic abnormalities, including diabetes, prediabetes, obesity, chronic kidney disease and hyperuricemia.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Coronary Artery Disease Diabetes Mellitus, Type 2 Dyslipidemias Obesity Metabolic Syndrome

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age 18-80 years
* Established coronary artery disease or metabolic disorders, including:

1. Type 2 diabetes diagnosed by one of the following criteria:

HbA1c \>/= 6.5% Fasting plasma glucose \>/= 7.0 mmol/l (confirmed) 2h plasma glucose value during OGTT \>/= 11.1 mmol/l Already receiving glucose-lowering agents
2. Prediabetes
3. Obesity
4. Chronic kidney disease
5. Hyperuricemia
6. Dyslipidemia

Exclusion Criteria

* Severe liver failure (Child-Pugh grade B to C)
* Severe anemia (hemoglobin \< 60g/L)
* Familial hypercholesterolemia
* Active malignant tumor
* Active autoimmune diseases on corticosteroids
* Acute or chronic infection
* Life expectancy \< 1 year
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ruijin Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

RUIYAN ZHANG

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Lin Lu, M.D., Ph.D.

Role: STUDY_DIRECTOR

Ruijin Hospital, Shanghai Jiaotong School of Medicine

Fenghua Ding, M.D., Ph.D.

Role: STUDY_CHAIR

Ruijin Hospital, Shanghai Jiaotong School of Medicine

Ruiyan Zhang, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Ruijin Hospital, Shanghai Jiaotong School of Medicine

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, , China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Xiaoqun Wang, M.D., Ph.D.

Role: CONTACT

+86 21 13651839760

Shuo Feng, M.D.

Role: CONTACT

+86 21 15921388296

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Jian Li, BS

Role: primary

0086 021 64370045

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

RJH-CAMPUS

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Cohort Study in Fujian Province
NCT06102187 RECRUITING