Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
189 participants
INTERVENTIONAL
2017-06-01
2021-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Calorie restricted diet and excecise intervention
a balanced diet that provided an energy deficit of 800 kcal/day from their daily energy requirement \[36\]. Macronutrient content of low caloric diet, expressed as percentage of ingested energy with carbohydrates 45-65%; fat 20-35%; and protein 10- 35%\[36\].Each session was approximately 150 minutes one week for six months and consisted of aerobic exercises, resistance training, and exercises to improve flexibility and balance.
Calorie restricted diet and exercise intervention
the calorie restricted diet were prescribed a balanced diet that provided an energy deficit of 800 kcal/day from their daily energy requirement.Macronutrient content of low caloric diet, expressed as percentage of ingested energy with carbohydrates 45-65%; fat 20-35%; and protein 10- 35%\[36\]. Participants were guided by a dietitian for adjustments of their caloric intake weekly for six months.Participants performed 1 or 2 sets at a resistance of approximately 65% of their one-repetition maximum, with 8 to 12 repetitions of each exercise; they gradually increased the intensity to 2 to 3 sets at a resistance of approximately 80% of their one-repetition maximum, with 6 to 8 repetitions of each exercise.
libitum diet and waiting list control group
participants then underwent a calorie of 2000 calorie above based on libitum free diets recommended to adults and normal physical activity without exercise during the program.
libitum diet and waiting list control group
libitum diet and waiting list control group, participants then underwent a calorie of 2000 calorie above based on libitum free diets recommended to adults and normal physical activity without exercise during the program.
Early APM group
Early APM group participants received APM with syndrome within 3 to 6 months
Early arthroscopic partial menisectomy group
Early APM group participants received APM with syndrome within 3 to 6 months
delayed APM group recruit participants with symptoms lasting for more than 6 months
delayed APM group recruit participants with symptoms lasting for more than 6 months
delayed APM group recruit participants with symptoms lasting for more than 6 months
delayed APM group recruit participants with symptoms lasting for more than 6 months
Interventions
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Calorie restricted diet and exercise intervention
the calorie restricted diet were prescribed a balanced diet that provided an energy deficit of 800 kcal/day from their daily energy requirement.Macronutrient content of low caloric diet, expressed as percentage of ingested energy with carbohydrates 45-65%; fat 20-35%; and protein 10- 35%\[36\]. Participants were guided by a dietitian for adjustments of their caloric intake weekly for six months.Participants performed 1 or 2 sets at a resistance of approximately 65% of their one-repetition maximum, with 8 to 12 repetitions of each exercise; they gradually increased the intensity to 2 to 3 sets at a resistance of approximately 80% of their one-repetition maximum, with 6 to 8 repetitions of each exercise.
libitum diet and waiting list control group
libitum diet and waiting list control group, participants then underwent a calorie of 2000 calorie above based on libitum free diets recommended to adults and normal physical activity without exercise during the program.
Early arthroscopic partial menisectomy group
Early APM group participants received APM with syndrome within 3 to 6 months
delayed APM group recruit participants with symptoms lasting for more than 6 months
delayed APM group recruit participants with symptoms lasting for more than 6 months
Eligibility Criteria
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Inclusion Criteria
* Clinical diagnosis of metabolic syndrome;
* Clinical diagnosis of 3 grade degneration meniscus leisons;
Exclusion Criteria
* Must be able to have no knee surgeries history;
* Must be able to have no rheumatoid arthritis or serious knee osteoarthritis with deformity;
* Must be able to have no contraindications to MRI;
* Must be able to have no severe cardiopulmonary disease;
* Must be able to have no musculoskeletal or neuromuscular impairments ;
* Must be able to have good visual, hearing, or cognitive;
35 Years
70 Years
ALL
Yes
Sponsors
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The First People's Hospital of Jingzhou
OTHER
Responsible Party
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Hongyu Wang
chief residents
Principal Investigators
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Hongyu Wang, Doctor
Role: PRINCIPAL_INVESTIGATOR
The First People's Hospital of Jingzhou
Locations
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First Affiliated Hospital of Jinzhou Medical University
Jinzhou, Liaoning, China
Countries
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Other Identifiers
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FirstJingzhou
Identifier Type: -
Identifier Source: org_study_id
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