The Effect of Wearing Masks on End-tidal Carbon Dioxide and Pulse Oximetry

NCT ID: NCT05114993

Last Updated: 2022-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

119 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-16

Study Completion Date

2022-01-27

Brief Summary

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An Interventional Study is planned with the primary purpose of screening for changes in end-tidal carbon dioxide (ETCO2), inspired carbon dioxide (ICO2), and other vital signs that may develop after donning a disposable surgical mask.

Measurements will be taken and recorded during a 5-minute control period without a mask, recording non-invasive ETCO2 and ICO2 levels by way of a nasal cannula (NC), oxygen saturation (SpO2), breaths per minute (RR), and heart rate (HR) via anesthesia equipment. This will be followed by a 15-minute intervention of wearing a disposable surgical mask and repeating measurements of ETCO2, ICO2, SpO2, RR, and HR, recorded each minute.

Data will be collected from adults and children as young as 2 years of age. Age groups will include children aged 2-14 and adults aged 18 to 80, as described in the details of the research protocol. Parents and their children are invited to participate together.

Detailed Description

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Conditions

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Carbon Dioxide

Study Design

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Allocation Method

NA

Intervention Model

SEQUENTIAL

Participants will be observed and monitored for 5 minutes without any intervention. After 5 minutes of observation and monitoring, participants will don a disposable surgical mask. Participants will then be observed and monitored for 15 minutes while under the intervention of "mask-wearing". Only one type of mask will be used for all participants.
Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Effects of donning a disposable surgical mask

Participants will be observed and monitored without wearing a mask for a 5-minute control period. Measurements will include End Tidal CO2, Inspired CO2, Pulse Oximetry, Respiratory Rate, and Heart Rate each minute without a mask x 5 minutes.

After 5 minutes, all study subjects will don the same model of disposable surgical mask. The same measurements will be taken, including End Tidal CO2, Inspired CO2, Pulse Oximetry, Respiratory Rate, and Heart Rate each minute with a mask x 15 minutes.

Group Type EXPERIMENTAL

wearing a disposable surgical mask

Intervention Type DEVICE

Physiologic vital signs will be monitored every minute for 5 minutes without a mask, followed by every minute for 15 minutes with a surgical mask.

Interventions

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wearing a disposable surgical mask

Physiologic vital signs will be monitored every minute for 5 minutes without a mask, followed by every minute for 15 minutes with a surgical mask.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Good health
* Aged 2 - 14 years (inclusive) or 18 - 80 years (inclusive)

Exclusion Criteria

* Significant cardiopulmonary diseases
* Intolerance to wearing nasal canula
* Intolerance to wearing a surgical mask
Minimum Eligible Age

2 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Missouri State University

OTHER

Sponsor Role collaborator

Patrick Brooks

OTHER

Sponsor Role lead

Responsible Party

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Patrick Brooks

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Missouri State University

Springfield, Missouri, United States

Site Status

Countries

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United States

References

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Brooks JP, Layman J, Willis J. Physiologic effects of surgical masking in children versus adults. PeerJ. 2023 Jun 16;11:e15474. doi: 10.7717/peerj.15474. eCollection 2023.

Reference Type DERIVED
PMID: 37342359 (View on PubMed)

Other Identifiers

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CT-2021-01

Identifier Type: -

Identifier Source: org_study_id

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