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Cigarette and E-cigarette Flavors Manipulations in the Experimental Tobacco Marketplace

NCT ID: NCT05110872

Last Updated: 2025-10-07

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

302 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-26

Study Completion Date

2021-08-13

Brief Summary

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This is a one-session study that participants complete remotely including consent, Experimental Tobacco Marketplace purchases, and assessments to examine the effects of cigarette and e-cigarette flavors on cigarette demand and substitution in the Experimental Tobacco Marketplace.

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Detailed Description

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This study uses a mixed design (within-subject repeated measures and between-group). Participants will be assigned to two different groups according to their preferred cigarette flavor (tobacco/menthol). Every participant will complete behavioral tasks and make hypothetical purchases of tobacco products in an online store under four different scenarios: a) e-cigarette flavor restricted and cigarette flavor restricted, b) e-cigarette flavor unrestricted and cigarette flavor restricted, c) e-cigarette flavor restricted and cigarette flavor unrestricted, d) e-cigarette flavor unrestricted and cigarette flavor unrestricted.

Conditions

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Tobacco Use Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Participants will complete different purchasing scenarios in the Experimental Tobacco Marketplace in which different cigarette and e-cigarette flavors are available. In all scenarios, a range of other tobacco products will also be available.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Investigators
The study design included automated randomization of the conditions per person at the time of completion, via Qualtrics Software.

Study Groups

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Menthol cigarette smokers

Adults (21 y.o. and older) who smoke ate least 10 menthol cigarettes per day will be recruited.

Group Type EXPERIMENTAL

Cigarette flavor restricted and e-cigarette flavor restricted

Intervention Type BEHAVIORAL

1. Tobacco cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Cigarette flavor restricted and e-cigarette flavor unrestricted

Intervention Type BEHAVIORAL

1. Tobacco cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored and a range of flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Cigarette flavor unrestricted and e-cigarette flavor restricted

Intervention Type BEHAVIORAL

1. Tobacco and menthol cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Cigarette flavor unrestricted and e-cigarette flavor unrestricted

Intervention Type BEHAVIORAL

1. Tobacco and menthol cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored and a range of flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Non-menthol cigarette smokers

Adults (21 y.o. and older) who smoke ate least 10 non-menthol cigarettes per day will be recruited.

Group Type EXPERIMENTAL

Cigarette flavor restricted and e-cigarette flavor restricted

Intervention Type BEHAVIORAL

1. Tobacco cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Cigarette flavor restricted and e-cigarette flavor unrestricted

Intervention Type BEHAVIORAL

1. Tobacco cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored and a range of flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Cigarette flavor unrestricted and e-cigarette flavor restricted

Intervention Type BEHAVIORAL

1. Tobacco and menthol cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Cigarette flavor unrestricted and e-cigarette flavor unrestricted

Intervention Type BEHAVIORAL

1. Tobacco and menthol cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored and a range of flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Interventions

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Cigarette flavor restricted and e-cigarette flavor restricted

1. Tobacco cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Intervention Type BEHAVIORAL

Cigarette flavor restricted and e-cigarette flavor unrestricted

1. Tobacco cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored and a range of flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Intervention Type BEHAVIORAL

Cigarette flavor unrestricted and e-cigarette flavor restricted

1. Tobacco and menthol cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Intervention Type BEHAVIORAL

Cigarette flavor unrestricted and e-cigarette flavor unrestricted

1. Tobacco and menthol cigarettes will be available in the Experimental Tobacco Marketplace
2. Tobacco-flavored and a range of flavored e-cigarettes will be available in the Experimental Tobacco Marketplace

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* currently smoke at least 10 cigarettes per day
* have smoked at least 100 cigarettes (lifetime), and
* are 21 years of age or older.

Exclusion Criteria

* inaccurate identification of usual brand of cigarette's as menthol or non-menthol
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Minnesota

OTHER

Sponsor Role collaborator

National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Virginia Polytechnic Institute and State University

OTHER

Sponsor Role lead

Responsible Party

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Roberta Freitas-Lemos

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Warren K Bickel, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Fralin Biomedical Research Institute at VTC

Locations

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Fralin Biomedical Research Institute

Roanoke, Virginia, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol, Statistical Analysis Plan, and Informed Consent Form

View Document

Other Identifiers

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P01CA217806

Identifier Type: NIH

Identifier Source: secondary_id

View Link

VT IRB# 20-827

Identifier Type: -

Identifier Source: org_study_id

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