Consumer Assessment of Tobacco Flavor and Odor

NCT ID: NCT04358315

Last Updated: 2026-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

29 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-03

Study Completion Date

2025-12-09

Brief Summary

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This trial studies consumer assessments of tobacco flavor and odor. This study will compare the ability of expert and consumer panels to identify and characterize flavors, determine threshold detection levels for individual and mixed flavors, and identify the dominant flavor of mixtures.

Detailed Description

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PRIMARY OBJECTIVE:

I. Develop consumer (untrained) sensory panels to identify and assess characterizing flavors in electronic (e)-liquids.

OUTLINE:

Non-user panelists smell and user panelists puff flavored e-liquids and answer questions about the products.

Conditions

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Current Vaper Healthy Subject

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Observational (smell or puff e-liquids)

All panel participants smell and user panelists puff flavored e-liquids and answer questions about the products.

Behavioral Intervention

Intervention Type BEHAVIORAL

Smell or puff e-liquids

Questionnaire Administration

Intervention Type OTHER

Ancillary studies

Interventions

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Behavioral Intervention

Smell or puff e-liquids

Intervention Type BEHAVIORAL

Questionnaire Administration

Ancillary studies

Intervention Type OTHER

Other Intervention Names

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Behavior Conditioning Therapy behavior modification Behavior or Life Style Modifications Behavior Therapy Behavioral Interventions Behavioral Modification Behavioral Therapy Behavioral Treatment Behavioral Treatments

Eligibility Criteria

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Inclusion Criteria

* CONSUMER USER: Current daily vapers of products containing nicotine
* CONSUMER USER: No concurrent use of other tobacco products
* CONSUMER USER: General good health
* CONSUMER USER: No allergies
* CONSUMER USER: No self-reported taste or smell deficits
* CONSUMER USER: Not pregnant or lactating
* CONSUMER USER: No medications known to interfere with taste/smell
* CONSUMER USER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
* CONSUMER USER: No positive diagnosis of COVID-19 within 30 days
* CONSUMER NONUSER: No use of tobacco or nicotine products in the last year
* CONSUMER NONUSER: General good health
* CONSUMER NONUSER: No allergies
* CONSUMER NONUSER: No self-reported taste or smell deficits
* CONSUMER NONUSER: Not pregnant or lactating
* CONSUMER NONUSER: No medications known to interfere with taste/smell
* CONSUMER NONUSER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
* CONSUMER NONUSER: No positive diagnosis of COVID-19 within 30 days

Exclusion Criteria

* CONSUMER USER: Outside age range
* CONSUMER USER: Not current daily vapers
* CONSUMER USER: Concurrent use of other tobacco products
* CONSUMER USER: Fair or poor general health
* CONSUMER USER: Allergies
* CONSUMER USER: Self-reported taste or smell deficits
* CONSUMER USER: Pregnant or lactating
* CONSUMER USER: Medications known to interfere with taste/smell
* CONSUMER USER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
* CONSUMER USER: Positive diagnosis of COVID-19 within 30 days
* CONSUMER NONUSER: Outside age range
* CONSUMER NONUSER: Use of tobacco or nicotine products in the last year
* CONSUMER NONUSER: Fair or poor general health
* CONSUMER NONUSER: Allergies
* CONSUMER NONUSER: Self-reported taste or smell deficits
* CONSUMER NONUSER: Pregnant or lactating
* CONSUMER NONUSER: Medications known to interfere with taste/smell
* CONSUMER NONUSER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests
* CONSUMER NONUSER: Positive diagnosis of COVID-19 within 30 days
Minimum Eligible Age

21 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

University of Rochester

OTHER

Sponsor Role collaborator

Roswell Park Cancer Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Richard J O'Connor

Role: PRINCIPAL_INVESTIGATOR

Roswell Park Cancer Institute

Locations

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Roswell Park Cancer Institute

Buffalo, New York, United States

Site Status

Countries

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United States

Other Identifiers

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NCI-2019-06320

Identifier Type: REGISTRY

Identifier Source: secondary_id

I 80518

Identifier Type: OTHER

Identifier Source: secondary_id

U54CA228110

Identifier Type: NIH

Identifier Source: secondary_id

View Link

I 80518

Identifier Type: -

Identifier Source: org_study_id

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