Automated Detection of Metastatic Bone Disease on Bone Scintigraphy Scans

NCT ID: NCT05110430

Last Updated: 2023-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2365 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-10

Study Completion Date

2021-12-31

Brief Summary

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Bone scintigraphy scans are two dimensional medical images that are used heavily in nuclear medicine. The scans detect changes in bone metabolism with high sensitivity, yet it lacks the specificity to underlying causes. Therefore, further imaging would be required to confirm the underlying cause. The aim of this study is to investigate whether deep learning can improve clinical decision based on bone scintigraphy scans.

Detailed Description

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Conditions

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Metastatic Bone Tumor

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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BS-UKA

Patients who underwent bone scintigraphy scanning between 2010 and 2018 at RTWH Aachen university hospital, and had a bone scan report that indicates the presence or absence of metastatic bone disease.

Deep learning based detection of metastatic bone disease on bone scintigraphy scans.

Intervention Type OTHER

The aim is to investigate whether deep learning algorithms can detect bone metastasis with high accuracy and specificity.

BS-Namur

Patients who underwent bone scintigraphy scanning between 2010 and 2018 at Namur university hospital, and had a bone scan report that indicates the presence or absence of metastatic bone disease.

Deep learning based detection of metastatic bone disease on bone scintigraphy scans.

Intervention Type OTHER

The aim is to investigate whether deep learning algorithms can detect bone metastasis with high accuracy and specificity.

BS-Aalborg

Patients who underwent bone scintigraphy scanning between 2010 and 2018 at Aalborg university hospital, and had a bone scan report that indicates the presence or absence of metastatic bone disease.

Deep learning based detection of metastatic bone disease on bone scintigraphy scans.

Intervention Type OTHER

The aim is to investigate whether deep learning algorithms can detect bone metastasis with high accuracy and specificity.

Interventions

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Deep learning based detection of metastatic bone disease on bone scintigraphy scans.

The aim is to investigate whether deep learning algorithms can detect bone metastasis with high accuracy and specificity.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients who underwent a bone scintigraphy scan that is available with the radiologic report between 2010-2018

Exclusion Criteria

* The lack of a bone scan, or corresponding radiologic report
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aalborg University Hospital

OTHER

Sponsor Role collaborator

Centre Hospitalier Universitaire de Liege

OTHER

Sponsor Role collaborator

University Hospital, Aachen

OTHER

Sponsor Role collaborator

University of Namur

OTHER

Sponsor Role collaborator

Maastricht University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Maastricht University

Maastricht, Limburg, Netherlands

Site Status

Countries

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Netherlands

References

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Ibrahim A, Vaidyanathan A, Primakov S, Belmans F, Bottari F, Refaee T, Lovinfosse P, Jadoul A, Derwael C, Hertel F, Woodruff HC, Zacho HD, Walsh S, Vos W, Occhipinti M, Hanin FX, Lambin P, Mottaghy FM, Hustinx R. Deep learning based identification of bone scintigraphies containing metastatic bone disease foci. Cancer Imaging. 2023 Jan 25;23(1):12. doi: 10.1186/s40644-023-00524-3.

Reference Type RESULT
PMID: 36698217 (View on PubMed)

Other Identifiers

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MBDDL

Identifier Type: -

Identifier Source: org_study_id

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