A Multi-Center Post-Market Data Collection Protocol to Evaluate the Performance of Orthofix Spine Devices

NCT ID: NCT05082090

Last Updated: 2025-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-15

Study Completion Date

2031-12-31

Brief Summary

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This protocol is designed to study Orthofix regulatory approved and commercially available spine devices to generate Real World Evidence (RWE) of device safety and performance in the treatment of patients with spine injuries and/or disorders following the local medical standard of care. The clinical data generated from this study will support compliance to global regulatory requirements including but not limited to the European Medical Device Regulation (EU MDR) for the applicable devices.

Detailed Description

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Conditions

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Spinal Disorders/Injuries

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Implanted with Orthofix Spinal products

Study will include 2000+ subjects implanted with Orthofix Spine devices including spine fixation systems and motion preservation systems (i.e. M6-C artificial cervical disc and M6-L artificial lumbar disc)

Spinal Surgery

Intervention Type PROCEDURE

Implanted with Orthofix Spinal products

Interventions

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Spinal Surgery

Implanted with Orthofix Spinal products

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Patient diagnosed with a spine injury/disorder and undergoing or has undergone spine procedure at the participating investigative centers utilizing Orthofix Spine devices.
2. Patient is 18 years or older at the time of surgery.
3. Patient is capable of understanding the content of the patient information / Informed Consent Form (ICF) for the prospective segment of the study.
4. Patient is willing and able to participate in the prospective data collection protocol and comply with the required data collection.

Note: For retrospective segment of the study: A waiver of consent for retrospective data collection is in place OR an informed consent is obtained from the participating patient prior to data collection as required by local regulations.

Exclusion Criteria

1\. Patient may be excluded from study participation if there are other concurrent medical or other conditions (chronic or acute in nature) that in the opinion of the participating investigator may prevent participation or otherwise render patient ineligible for the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Orthofix Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Cahit Akbas

Role: STUDY_DIRECTOR

Global Clinical Program Manager

Locations

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Lanman Spinal Neurosurgery

Beverly Hills, California, United States

Site Status

RasouliSpine

Beverly Hills, California, United States

Site Status

Neurosurgical Medical Clinic

San Diego, California, United States

Site Status

Acadiana Neurosurgery

Lafayette, Louisiana, United States

Site Status

Columbus Orthopaedic

Columbus, Mississippi, United States

Site Status

M3 Emerging Medical Research

Durham, North Carolina, United States

Site Status

University Orthopedics

East Providence, Rhode Island, United States

Site Status

Summit Brain, Spine and Orthopedics

Lehi, Utah, United States

Site Status

Tuckahoe Orthopedics

Richmond, Virginia, United States

Site Status

Marien-Krankenhaus Bergisch Gladbach

Bergisch Gladbach, , Germany

Site Status

Stenum Ortho GmbH

Ganderkesee, , Germany

Site Status

Praxis für Neurochirurgie-Chirotherapie

Nordhausen, , Germany

Site Status

Orthopädikum Potsdam

Potsdam, , Germany

Site Status

Krankenhaus Maria-Hilf Stadtlohn

Stadtlohn, , Germany

Site Status

The Club Surgical Centre

Pretoria, , South Africa

Site Status

Zuid-Afrikaans Hospital

Pretoria, , South Africa

Site Status

Hospital Clínic de Barcelona

Barcelona, , Spain

Site Status

Hospital Vall d'Hebron

Barcelona, , Spain

Site Status

Hospital Universitario Son Espases

Palma de Mallorca, , Spain

Site Status

University Hospital Marqués de Valdecilla

Santander, , Spain

Site Status

Countries

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United States Germany South Africa Spain

Other Identifiers

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CP-2001SPPM

Identifier Type: -

Identifier Source: org_study_id

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