fMRI Feasibility Older Hip Fracture Surgery

NCT ID: NCT05081726

Last Updated: 2022-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-04

Study Completion Date

2022-12-06

Brief Summary

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An assessment of the feasibility of structural and functional magnetic resonance imaging (MRI) brain scans in older people who have recovered from and older people who never had delirium after hip fracture surgery

Detailed Description

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Postoperative delirium, an acute sate of confusion occurs with higher frequency in older people. Hip fracture surgery is a procedure associated with an increased risk of postoperative delirium.

In the study the feasibility of achieving structure and functional connectivity imaging of the brain, using magnetic resonance imaging, in older people who are recovering from hip fracture surgery will be assessed.

People who have recovered from post operative delirium and people who did not have postoperative delirium will be included.

Conditions

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Magnetic Resonance Imaging Hip Fractures Postoperative Delirium

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Never had delirium

Older people recovering from hip fracture surgery who did not have postoperative delirium

Functional MRI

Intervention Type DIAGNOSTIC_TEST

Series of MRI scans of the brain

Recovered delirium

Older people recovering from hip fracture surgery who experienced delirium which has resolved

Functional MRI

Intervention Type DIAGNOSTIC_TEST

Series of MRI scans of the brain

Interventions

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Functional MRI

Series of MRI scans of the brain

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 65 years
* Cognitively intact
* primary admission for hip fracture surgery

Exclusion Criteria

* Cognitive impairment
* Less than moderate level of activities of daily living
* History of neurosurgery/significant head trauma
* Acutely unwell/moribund
* Presence of neurological diseases including overt stroke, dementia, multiple sclerosis, Parkinson's disease, intracranial tumours and other significant neurologic disorders.
* Postural or movement disorders likely to impede MRI scan
* Contraindications to MRI
* Complex fractures/multiple injuries
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Nottingham

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rob Dineen, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Nottingham

Central Contacts

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Abiodun Moronke Noah, FRCA

Role: CONTACT

01158231011

Iain K Moppett, DM

Role: CONTACT

01158230959

Other Identifiers

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19087

Identifier Type: -

Identifier Source: org_study_id

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