Virtual Reality VAlidation Tool for Cognitive Rehabilitation, Oriented Project for People With Psychosocial Disabilieties

NCT ID: NCT05070065

Last Updated: 2023-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-10

Study Completion Date

2022-02-10

Brief Summary

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Randomized controlled open-label cross-over clinical feasibility study with waiting list, 60 people will be recruited from the Consultation and Psychosomatic Psychiatry Center of the University Hospital of Cagliari (San Giovanni di Dio Civil Hospital) with a diagnosis of mental disorder. The investigators propose a VR intervention of 3 months with 2 weekly session of CEREBRUM (cognitive remedy intervention with virtual reality) first to the group A and then to the group B.

Detailed Description

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Background: Cognitive remedial interventions have been found to be effective in the treatment of various psycho-social disorders. The use of Virtual reality as a rehabilitation tool has been showing various scientific evidences in recent years like in cardiovascular, neurological and musculoskeletal rehabilitation. In mental health evidence they seem to be concentrated in the rehabilitation of social cognition in people with schizophrenia diagnosis and psychotherapy. The aim of this study is to evaluate the feasibility and the effectiveness of the first Cognitive Remedial toll in Virtual Reality (CEREBRUM) for people that has experienced in mental health.

Methods: Randomized controlled open-label cross-over clinical feasibility study with waiting list, 60 people will be recruited from the Consultation and Psychosomatic Psychiatry Center of the University Hospital of Cagliari (San Giovanni di Dio Civil Hospital) with a diagnosis of mental disorder. The investigators propose a intervention of 3 months with 2 weekly session of CEREBRUM first to the group A and then to the group B

Conditions

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Mood Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Randomized controlled open-label cross-over clinical feasibility study with waiting list
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
people with psychosocial disabilities

Study Groups

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virtual reality

The experimental group A receives the cognitive remedy intervention with virtual reality (CEREBRUM)

Group Type EXPERIMENTAL

Cognitive remedy intervention with virtual reality (CEREBRUM)

Intervention Type DEVICE

Cognitive Remedial method Virtual Reality (CEREBRUM)

waiting list

waiting list

Group Type OTHER

Cognitive remedy intervention with virtual reality (CEREBRUM)

Intervention Type DEVICE

Cognitive Remedial method Virtual Reality (CEREBRUM)

Interventions

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Cognitive remedy intervention with virtual reality (CEREBRUM)

Cognitive Remedial method Virtual Reality (CEREBRUM)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age from 18 to 75;
* Diagnosis of psychosis and / or mood disorder according to DSM-IV (American Psychiatric Association, 2000).
* both sexes;
* users who sign the informed consent;
* users under protection for which the informed consent is signed by the guardian

* The diagnosis of epilepsy or serious eye diseases, due to the risk associated with the excessive stimulation of virtual reality
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Cagliari

OTHER

Sponsor Role lead

Responsible Party

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Mauro Giovanni Carta

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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P.O. San Giovanni di Dio, AOU Cagliari

Cagliari, , Italy

Site Status

Countries

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Italy

References

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Sancassiani F, Perra A, Galetti A, Di Natale L, De Lorenzo V, Lorrai S, Kalcev G, Pintus E, Cantone E, Nonnis M, Nardi AE, Montisci R, Primavera D. Alexithymia and Bipolar Disorder: Virtual Reality Could Be a Useful Tool for the Treatment and Prevention of These Conditions in People with a Physical Comorbidity. J Clin Med. 2024 Oct 18;13(20):6206. doi: 10.3390/jcm13206206.

Reference Type DERIVED
PMID: 39458156 (View on PubMed)

Perra A, De Lorenzo V, Zaccheddu R, Locci A, Piludu F, Preti A, Di Natale L, Galetti A, Nardi AE, Cossu G, Sancassiani F, Barbato S, Cesaretti O, Kurotshka PK, Carta MG. Cognitive Remediation Virtual Reality Tool a Recovery-Oriented Project for People with Bipolar Disorder: Protocol of a Feasibility Randomized Clinical Trial. Clin Pract Epidemiol Ment Health. 2022 Oct 6;18:e174501792208220. doi: 10.2174/17450179-v18-e2208220. eCollection 2022.

Reference Type DERIVED
PMID: 37274852 (View on PubMed)

Perra A, Galetti A, Zaccheddu R, Locci A, Piludu F, Preti A, Primavera D, Di Natale L, Nardi AE, Kurotshka PK, Cossu G, Sancassiani F, Stella G, De Lorenzo V, Zreik T, Carta MG. A Recovery-Oriented Program for People with Bipolar Disorder through Virtual Reality-Based Cognitive Remediation: Results of a Feasibility Randomized Clinical Trial. J Clin Med. 2023 Mar 9;12(6):2142. doi: 10.3390/jcm12062142.

Reference Type DERIVED
PMID: 36983145 (View on PubMed)

Other Identifiers

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Prot. PG/2020/7577

Identifier Type: -

Identifier Source: org_study_id

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