Effectiveness of a Cognitive Remediation Intervention Based on Virtual Reality for Promotion of Cognitive Functioning and Participation in Daily Life Among Persons With Affective Disorder

NCT ID: NCT04288609

Last Updated: 2020-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-03-31

Study Completion Date

2020-12-01

Brief Summary

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The purpose of this study is to test the efficacy of remedial cognitive intervention using The Functional Brain Trainer VR (FBT, Intendo ©) to improve cognitive functioning, participation in daily life occupations, and functional capacity in the field of IADL among people with affective disorders receiving inpatient and daycare mental-health services.

Detailed Description

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This study is an experimental study, in a pre-post design with a control group, the sampling is convenience. The study will include 40 people aged 18-60 with a diagnosis of Affective disorder based on DSM-5.

Inclusion criteria: age 18-60, Diagnosis of Major Depression or Bipolar disorder based on DSM-5; Mood stabilizing medication for at least 2 weeks, Exclusion criteria: Neurological disorders and neurodevelopmental conditions in addition to mental health diagnosis; Physical disability in addition to mental health conditions; Psychotic state; active substance abuse; custodian.

They will be recruited from active inpatient and daycare wards of the "Geha Mental Health Center", Israel and will be randomly allocated into two groups: experimental and control. An experimental group will attend 6 VR based cognitive remediation sessions of 30 minutes for training response inhibition, self-initiation, cognitive flexibility, sustained attention, divided attention, working memory, planning, persistence. The control group will complete 6 sessions of 30 minutes of low-tech (paper and pencil tasks) remedial training of the same cognitive components. These in addition to routine care. The evaluation for symptoms severity, cognition, functional capacity and participation in daily life activities will be conducted at the beginning of the study and after about 4 weeks.

Conditions

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Affective Disorder

Keywords

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affective disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
single

Study Groups

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Intendu FBT inpatient

Motion Based Cognitive Video Games Software

Group Type EXPERIMENTAL

Intendu

Intervention Type OTHER

Cognitive remediation using VR adaptive platform for response inhibition, self-initiation, cognitive flexibility, sustained attention, divided attention, working memory, planning, persistence.

paper and pencil tasks

paper and pencil tasks

Group Type ACTIVE_COMPARATOR

Paper and Pencil cognitive remediation training

Intervention Type OTHER

Cognitive remediation using paper and pencil tasks for response inhibition, self-initiation, cognitive flexibility, sustained attention, divided attention, working memory, planning, persistence.

Interventions

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Intendu

Cognitive remediation using VR adaptive platform for response inhibition, self-initiation, cognitive flexibility, sustained attention, divided attention, working memory, planning, persistence.

Intervention Type OTHER

Paper and Pencil cognitive remediation training

Cognitive remediation using paper and pencil tasks for response inhibition, self-initiation, cognitive flexibility, sustained attention, divided attention, working memory, planning, persistence.

Intervention Type OTHER

Other Intervention Names

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Motion Based Cognitive Video Games Software Low-Tech remedial training

Eligibility Criteria

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Inclusion Criteria

* Age 18-60,
* Diagnosis of Major Depression or Bipolar disorder based on DSM-5;
* Mood stabilizing medication for at least 2 weeks,

Exclusion Criteria

* Neurological disorders and neuro-developmental conditions in addition to mental health diagnosis;
* Physical disability in addition to mental health conditions;
* Psychotic state;
* active substance abuse;
* custodian
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tel Aviv University

OTHER

Sponsor Role collaborator

Geha Mental Health Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Gilad Eger, PhD

Role: CONTACT

Phone: +972523520180

Email: [email protected]

Dovrat Cohen, BOT

Role: CONTACT

Phone: +972526763854

Email: [email protected]

Other Identifiers

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Geha Mental Health Center

Identifier Type: -

Identifier Source: org_study_id